TWiV explains how vaccine-induced thrombotic thrombocytopenia develops from antibodies to adenovirus and somatic hypermutation, and castration by a viral protein tyrosine phosphatase that targets a host cell cycle checkpoint protein.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker

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Links for this episode

• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• US repeals environmental endangerment finding (Nature)
• Environmental groups sue EPA (Guardian)
• NIAID to drop pandemic preparedness and biodefense (Nature)
• FDA backpedals on Moderna mRNA rejection (npr)
• Mechanism of VITT (NEJM)
• Parasitc castration by a wasp virus protein (PNAS)
• Polydnaviruses (PloS Path)
• Timestamps by Jolene Ramsey. Thanks!

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Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.