
Learning Bayesian Statistics
·S1 E146
Lasers, Planets, and Bayesian Inference, with Ethan Smith
Episode Transcript
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Today we are heading straight into the heart of high-energy density physics.
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The place where lasers crush matter, astrophysics meets the lab, and Bayesian inference
becomes indispensable.
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My guest is Ethan Smith, a PhD candidate at the University of Rochester, working at the
intersection of plasma spectroscopy, diagnostics, technology, and Bayesian data.
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analytics.
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studies what happens when you use some of the world's most powerful lasers to squeeze
matter to extreme conditions, the same conditions you would find inside planets, stars, or
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supernovae.
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This is an episode for anyone who loves physics, who loves patient methods, or who just
wants to hear how scientific discovery actually happens behind the scenes.
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This is Learning Vision Statistics, episode 146, recorded.
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October 7, 2025.
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Welcome to Learning Bayesian Statistics, a podcast about Bayesian inference, the methods,
the projects, and the people who make it possible.
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I'm your host, Alex Andorra.
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You can follow me on Twitter at alex-underscore-andorra.
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like the country.
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For any info about the show, learnbasedats.com is Laplace to be.
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Show notes, becoming a corporate sponsor, unlocking Bayesian Merge, supporting the show on
Patreon, everything is in there.
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That's learnbasedats.com.
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If you're interested in one-on-one mentorship, online courses, or statistical consulting,
feel free to reach out and book a call at topmate.io slash Alex underscore and Dora.
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See you around, folks.
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and best patient wishes to you all.
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And if today's discussion sparked ideas for your business, well, our team at Pimc Labs can
help bring them to life.
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Check us out at pimc-labs.com.
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Ethan Smith, welcome to Learning Basian Statistics.
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Thank you for having me.
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Thrill the beer.
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Yeah, it's great to have you here.
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Thanks a lot to JJ Ruby for putting us in contact.
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I hear you guys are doing some fun stuff at Rochester, doing some physics things.
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We'll definitely talk about that.
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First, both your first and last name are very challenging for me to say with an English
accent as a French
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man, because I want to say Ethan Smith.
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Uh, and so it's very hard for me to say Ethan Smith.
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It's like twice to the age in a row.
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That's like, making my life hard.
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apologize for that.
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Yeah.
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That's, that's my bad.
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I do like, I do love the name Ethan that that sounds really good in English in French.
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I don't like it's etan, but Ethan sounds really like very classy.
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Yes, I agree.
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Unfortunately, it's a very common name.
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uh There is another Ethan Smith in my field and we go to lot of the same conferences and
it causes a lot of issues.
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Yeah.
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Yeah.
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I am not surprised.
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will confess that while I was preparing for the episode, um looking you up on the internet
was not easy because there was a lot of Ethan Smithies.
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And if you input Ethan Smiths Rochester, um
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There is actually one Ethan Smith who unfortunately died in a plane crash.
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Yeah, from Rochester, Minnesota.
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Yeah, exactly.
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I know him.
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damn.
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Yeah.
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So I was reading up on that.
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was like, damn, this is a very sad story.
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Not me though.
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Different Ethan.
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I'm still alive.
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Yeah, thankfully.
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So yeah, like actually, let's say talking about you.
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Let's start talking about you.
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um
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So always when I, when I start asking to the guests says, think, you know, because, uh,
you listened to the show, you told me.
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And so I very, very grateful for that.
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and so I know, you know, you do a lot of cool stuff, um, listeners don't, you don't know
yet.
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So yeah, just give us the, the origin story.
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What are you doing nowadays and how did you end up working on that?
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Yeah.
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So I'm getting, I'm finishing up my PhD.
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at the University of Rochester.
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um Specifically, I'm in the field of high energy density physics, uh which is sort of a uh
niche subfield uh in physics where we use extremely high powered lasers to compress matter
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to some extremely distressing conditions.
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And it turns out when you compress matter with lasers, can...
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you know, recreate some of the states that you would find, for example, at the center of
giant planets, or even in some cases at the center of stars.
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And so that lets you recreate these systems in the laboratory and directly study how they
behave uh sort of at a much smaller scale than you can with observational astronomy.
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And so that lets you learn a lot about the material properties of these astrophysical
objects.
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And it also lets you create some just really interesting states of matter that you can't
find anywhere else on earth or even sometimes in the universe.
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um And so, we create these very hot, dense states of matter for a billionth of a second.
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And what the focus of my work is on is understanding how do you make a measurement, one,
how do you make a measurement of a system that that extreme and exists for a very short
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amount of time?
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And two, how do you interpret those measurements?
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So measurements that we get out of these systems are often very integrated.
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ah know, there's this inverse problem of trying to take up, know, you have an image of
this plasma that you've created and you have to try and back out what was the temperature
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and density of this, you know, miniature sun we've created in the laboratory.
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And so that's sort of the thrust of my PhD is trying to use data science techniques,
including of course, know, Bayesian inference.
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to take this set of uh information-rich but complicated measurements and understand what's
happening in these experiments.
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um And so we've learned a lot.
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uh J.J.
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Ruby, who was on the show before, was sort of got the ball rolling with thinking about
using Bayesian inference in this context.
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And I've sort of inherited a lot of his work and carried it on to the next generation of
grad student.
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And then I'm sure some grad student will come after me
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and carry it even further, hopefully.
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Oh, I didn't answer the second part of your question, which is how did I end up doing
this?
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Which is a fair question, because it's very, when I tell people what I do, they're like,
how did you even know that you could do that?
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ah And so I grew up in Rochester, New York, not Minnesota.
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ah And at the University of Rochester, we have two of the largest lasers in the world.
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They're actually the largest lasers at any academic facility anywhere.
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And those are the Omega 60 and Omega EP lasers.
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They're very impressive if you ever are in town and you want to come, you know, take a
tour.
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Each of these lasers is about the size of a football field.
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uh And, you know, we take these massive lasers and focus them down onto a, tiny point.
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uh And it's very impressive.
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And so, you know, I went to school in the area.
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I went and toured.
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these facilities as part of my undergraduate research program.
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And so I was like, oh, that's really cool.
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I didn't really think anything of it.
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Like, of course this giant laser would be in Rochester.
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Yeah, like that makes sense.
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And then I was, you know, I decided to apply to grad school and I was, you know,
considering the University of Rochester, but I didn't want to really stay.
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I wanted to go, you know, go somewhere else.
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But then I met Rip Collins, who is my current advisor at a conference in Fort Lauderdale
of all places.
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And he told me about the cool science that they were doing with those lasers, know, all of
the high energy density physics, the planetary science that you can do with these things.
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And that really, you know, sort of convinced me that, yeah, like this is, you know, this
is even cooler than you might suspect by the fact that there's these football field size
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lasers.
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You can actually do really interesting science with these.
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And that sort of inspired me to go down that road and then, you know, ended up working
with him for the past, ooh.
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on five years now.
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So it's been an experience, been a wild ride, doing a lot of laser experiments.
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Yeah.
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Okay.
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So you were attracted by the big shiny laser, basically.
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This was an important role.
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I'll say the lasers themselves are impressive, but I didn't have any interest in...
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using them because I wasn't super motivated by the main uh mission of the laboratory for
laser energetics, which is where these football field sized lasers are, is the pursuit of
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fusion energy, which is great and I think a worthwhile endeavor, but it ah didn't move me
because it's just about uh effectively making as many neutrons as you can from fusion.
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And you just want that number to go up.
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And that to me always felt like more of an engineering problem than a physics problem.
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ah And so when you go and tour these facilities, a lot of emphasis is placed on this
fusion uh arm of the program.
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And so what really inspired me was the physics of it all, right?
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To make the number of neutrons go up, you need to really understand the physics of these
very extreme systems that exist at millions or billions of atmospheres of pressure.
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And that's a very interesting and difficult problem from a theoretical standpoint and from
an experimental standpoint and statistical analysis.
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And so that's what really got me interested.
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And then, you know, I met JJ through that and he got me interested in Bayesian inference,
um which is an even more interesting subset of an interesting problem.
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So I would say the Bayesian inference at the end of the day is what got me more than the
giant lasers.
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Hmm.
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Okay.
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Interesting.
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So thanks JJ first and second.
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oh So basically the, like the physics was here from a very, from the very beginning,
right?
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So, um, yeah, can you also share your path into physics and, um, how did you first get
interested in that?
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What was also your undergraduate training like and how do you think that shaped your
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your research direction today.
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Yeah, sure.
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So I took a pretty straightforward path.
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you know, took science classes in high school.
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I liked it.
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I came from a very liberal arts family.
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So my parents are both teachers.
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My dad taught history and my mom's an English professor.
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And so, you know, sort of teaching is the family business in my family.
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And so I had always assumed I would go teach.
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But I knew I didn't want to do English or history or any of these liberal arts things
because I hated writing.
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uh And so I wanted to do, you know, I liked science and math a lot more.
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um And so my family was always like, well, what are you going to do with that?
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What are you going to, you know, a science degree?
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What use is that?
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You know, you know, and so I went into undergrad.
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went to uh SUNY Geneseo, which is about, you know, 40 minutes outside of Rochester.
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So very far from home for me.
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ah
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I, you know, I had taken physics most recently, uh, as a, know, junior and senior in high
school and I really liked it.
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So I said, well, we'll keep, we'll keep, you know, stick with it.
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And so I majored in it and I really liked in, in, uh, college as an undergrad.
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The plan was to go into, um, teach high school teaching.
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So I was gonna, you know, enroll in the education school there and then do that.
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But then I decided that.
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That's not what I wanted to do.
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And so I started um doing research, undergraduate research with a physics professor at
Geneseo, Kurt Fletcher, shout out.
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And um that's, I mean, that's where I really learned, you know, that I could do science
and that doing science is really fun.
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So that was a much more hands-on research project that I did in undergrad, turning
wrenches.
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And we were building uh a spectrometer for, you know, ion backscattering studies or
whatever.
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And, you know, that's, that's when I fell in love with science and doing science, both
from a hands-on perspective and just, you know, thinking about science is, is a really
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interesting and rewarding pastime.
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And so then I was like, well, maybe I should do more of this.
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And so, you know, I applied to grad school, got in, and then I've, you know, been doing it
for uh five and a half years now and probably going to do more of it after this.
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So I think that's, that's sort of the.
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the timeline for me.
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It's always just been like, ah, there's probably more science to know, more physics to do.
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And so it's been a rewarding process so far.
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Yeah, we'll see.
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Yeah.
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Um, that, makes total sense.
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I can, yeah, I can vouch for your, uh, your passion for the, the topic.
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I'm also going to bet that you're going to do that for, for a long time.
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and so actually what, what you already talked about is that your research lies and the
intersection of high energy density physics.
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plasma spectroscopy and vision inference.
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So could you give us a big picture of what that looks like, of what your current portfolio
project is?
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Because I'm guessing that lot of listeners are not familiar with high energy density
physics and plasma spectroscopy.
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That's very fair.
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High energy density physics is an interesting one because it exists at the intersection of
a lot of fields, right?
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Because you have these very hot, dense
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balls of plasma, you have plasma science going on, you have laser science because you're
using these giant lasers, you have to know how to use those and how to compress things
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effectively.
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And then of course, you know, how do you make a measurement?
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Well, these things get really hot, they emit x-rays, they emit neutrons from fusion
reactions, and so you have to understand nuclear physics, you have to understand atomic
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physics, and all these things.
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And so sort of
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At a high level, uh the kind of high energy density physics experiments I work on are
spherical implosions.
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So you can think of uh the standard high energy density physical experiment is you take a
planar foil, a piece of material, metal, and you just whack it on one side of the laser,
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drive a shockwave through it, and compress it that way.
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And that lets you get up to millions of atmospheres of pressure, which is uh unreasonable
conditions.
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And it turns out that there's sort of a limit to how hard you can hit something with a
laser ah before you just start, you know, dumping all this energy into nonlinear
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instabilities and whatnot.
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And so a way to get to higher pressure is to do it in convergent geometry, which
essentially means you'd take your laser illumination from one side and you illuminate a
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spherical target from all sides.
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And so now...
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Instead of getting compression in one dimension, you're getting compressions in all three
dimensions, right?
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And so that lets you, know, exponentially amplify the pressures you can reach up to, you
know, billions, billions of atmospheres, hundreds of billions of atmospheres even.
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And so those, uh those convergent systems are even harder to measure.
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At least in a planar geometry, you can, you know, measure something from the backside of
your target and maybe get a direct measurement of how fast it's going.
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But in these experiments,
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You know, it's complete.
213
00:16:51,106 --> 00:16:52,987
All your measurements are completely integrated.
214
00:16:52,987 --> 00:16:56,988
The X-rays that you measure from these have to travel through the target itself.
215
00:16:56,988 --> 00:17:02,049
So you have to already know what temperature and density the target's at to understand
those X-rays.
216
00:17:02,189 --> 00:17:12,512
And so the, the sort of, main focus of, of my research is understanding what's happening
in that 10 million degree ball of fire.
217
00:17:12,512 --> 00:17:17,174
You know, it's a spherical plasma that's emitting X-rays and neutrons and all this stuff.
218
00:17:17,174 --> 00:17:18,934
How do you understand how you image it?
219
00:17:18,934 --> 00:17:21,665
ah How do you understand the spectra that come out of it?
220
00:17:21,665 --> 00:17:21,906
Right?
221
00:17:21,906 --> 00:17:32,812
If you have bound electrons in there, they're emitting, you know, the characteristic
emission like you see, uh I guess in science class, when you look at the neon lights, for
222
00:17:32,812 --> 00:17:34,382
example, the fluorescent lights.
223
00:17:34,382 --> 00:17:45,429
ah But how do those, you know, how do those lines change when you're compressed to 10
billion atmospheres of pressure and you're at 10 million degrees Kelvin?
224
00:17:45,429 --> 00:17:48,690
Like the atomic physics of that are challenging.
225
00:17:48,982 --> 00:17:53,824
But you can measure those transitions and you can learn a lot about the system from that.
226
00:17:53,984 --> 00:17:58,826
And so then the question is, how do you measure these systems?
227
00:17:58,826 --> 00:17:59,947
What do you measure?
228
00:17:59,947 --> 00:18:03,088
And then what measurements give you the most information?
229
00:18:03,088 --> 00:18:13,753
ah And so that's where the sort Bayesian inference comes in and working in an information
content sort of paradigm where you take all these measurements, you take X-ray pictures,
230
00:18:13,753 --> 00:18:17,364
you take uh spectrographs of these systems.
231
00:18:17,962 --> 00:18:20,554
What information can you get and what's the sort of max?
232
00:18:20,554 --> 00:18:23,185
There's a certain number of measurements you can make, right?
233
00:18:23,185 --> 00:18:25,606
You're limited by space on the target chamber.
234
00:18:25,606 --> 00:18:38,734
ah And so understanding the information content of each measurement and what's the most
effective combination is something that is very non-trivial and something that I'm looking
235
00:18:38,734 --> 00:18:40,074
into actively.
236
00:18:40,134 --> 00:18:46,798
And then the third piece of it is sort of what discoveries can we make with these tools,
right?
237
00:18:47,366 --> 00:18:53,029
you know, we have these Bayesian statistics, we have all of these images and spectroscopy.
238
00:18:53,029 --> 00:18:57,252
uh What physics discoveries can we make and, you what can we do?
239
00:18:57,252 --> 00:19:04,695
How does that uh translate to our understanding of astrophysical systems and, you know,
the universe at large?
240
00:19:05,116 --> 00:19:16,102
And I think that's really the most interesting part is we build all these really uh
complicated tools to all these fancy statistics and whatnot.
241
00:19:16,214 --> 00:19:28,103
uh to sort of peer inside these extreme systems and understand really what's going on, not
only in these systems, but in other extreme astrophysical systems.
242
00:19:28,103 --> 00:19:39,661
so there's a lot of interesting discoveries that are coming out of that about atomic
physics, about nuclear physics, about what role does radiation play, right?
243
00:19:39,661 --> 00:19:43,493
You're producing an enormous amount of photons.
244
00:19:43,493 --> 00:19:44,252
uh
245
00:19:44,252 --> 00:19:46,883
just because you have this hot, dense ball of gas.
246
00:19:46,883 --> 00:19:51,526
And those, you can produce enough photons to affect the dynamics of the system.
247
00:19:51,526 --> 00:19:55,448
The radiation flux is so large that the system behaves differently.
248
00:19:55,448 --> 00:20:06,773
And understanding that is very non-trivial because a lot of these, you know, systems can't
be created anywhere else uh except, you know, here in the lab and understanding that is
249
00:20:06,773 --> 00:20:07,394
very difficult.
250
00:20:07,394 --> 00:20:14,397
So all of this requires some level of, you know, statistical inference.
251
00:20:14,405 --> 00:20:23,310
And that's really what my, the big picture of my work is building the tools to do that
statistical inference.
252
00:20:23,991 --> 00:20:32,265
Because you can make the analog very similar uh type of experiment in particle physics at
particle colliders.
253
00:20:32,265 --> 00:20:34,917
You have very distressing conditions there as well.
254
00:20:34,917 --> 00:20:40,620
Although those are at order of magnitude higher energy than we can produce with our laser
systems.
255
00:20:40,620 --> 00:20:43,081
um
256
00:20:43,323 --> 00:20:55,293
To understand what comes out of those violent particle collisions where you're at, know,
GEV, TEV energies requires very complex statistical tools, very high level understanding
257
00:20:55,293 --> 00:21:00,347
of your detector and very good models of those physical systems.
258
00:21:00,428 --> 00:21:08,184
And, you know, they're sort of the particle physics field is a lot further along down this
road than we are.
259
00:21:08,184 --> 00:21:12,047
And so we have to sort of, we're starting from a very much lower level.
260
00:21:12,101 --> 00:21:22,487
And so we have to understand uh from a fundamental level, the physics of the system, the
detector, and how to do that inference rigorously.
261
00:21:24,111 --> 00:21:27,884
Yeah, this is just fascinating.
262
00:21:27,984 --> 00:21:33,409
So concretely, what does that look like to work with that kind of data?
263
00:21:33,409 --> 00:21:36,461
First, what does your data look like?
264
00:21:36,461 --> 00:21:37,712
Where do they come from?
265
00:21:37,712 --> 00:21:41,816
um What's the size of them?
266
00:21:41,816 --> 00:21:50,943
How does it look like to concretely work on these kind of projects before we dive a bit
more into the modeling complexities?
267
00:21:50,943 --> 00:21:51,564
Yeah, sure.
268
00:21:51,564 --> 00:21:53,007
oh
269
00:21:53,007 --> 00:21:54,718
That's a good question.
270
00:21:54,718 --> 00:22:09,426
The data oftentimes looks like a uh dot on a camera, like a little spherical blob, or
maybe if you're lucky, a series of spherical blobs that correspond to different times.
271
00:22:09,426 --> 00:22:22,743
um Or if you're even luckier, you could get maybe a streaked continuous record in time
with one of these streak cameras that we've developed in the field.
272
00:22:22,961 --> 00:22:32,315
uh And what it looks like is trying to build a sort of generative model of these blobs.
273
00:22:32,315 --> 00:22:36,517
So using our best available knowledge of the physics, right?
274
00:22:36,517 --> 00:22:38,728
We think we understand hydrodynamics.
275
00:22:38,728 --> 00:22:43,940
We think maybe we understand how X-rays are produced in plasmas and how they propagate.
276
00:22:43,940 --> 00:22:52,413
That may or may not be true, but we can take our best available models and try and build
277
00:22:52,441 --> 00:23:01,145
a generative model of how the physics, we think the physics will evolve and how that will
manifest in the observed emission.
278
00:23:01,586 --> 00:23:07,549
And then we need to also understand how our detector is constructing that blob.
279
00:23:07,549 --> 00:23:16,304
And so that requires knowing what the resolution is and the sensitivity to different
energies of X-rays and as well as the statistics, right?
280
00:23:16,304 --> 00:23:18,395
And that's the most complicated part.
281
00:23:18,395 --> 00:23:22,175
And something that we're really working on is understanding
282
00:23:22,175 --> 00:23:26,886
you know, if you have a given X-ray flux, what signal, what distribution of signals are
you going to measure?
283
00:23:26,886 --> 00:23:34,878
And, know, you have Poisson counting statistics for how many photons are absorbed, but
then the rest of it is a complete mess because it's so complicated.
284
00:23:34,878 --> 00:23:38,848
And you're trying to make a measurement in a fraction of a billionth of a second.
285
00:23:38,969 --> 00:23:43,520
And so all hell breaks loose basically, the statistics get very complicated.
286
00:23:43,520 --> 00:23:46,991
There's correlations between neighboring data points.
287
00:23:46,991 --> 00:23:49,804
And so understanding that is a really
288
00:23:49,804 --> 00:23:52,804
sort of nuanced and complicated piece of it.
289
00:23:52,804 --> 00:24:02,404
But all of it is just to produce this little, you know, dot on your camera, basically,
which has an intensity, it's got a radius, maybe it's got some shape, but it's very simple
290
00:24:02,404 --> 00:24:03,084
data.
291
00:24:03,084 --> 00:24:06,244
We're using technology from the 1800s.
292
00:24:06,244 --> 00:24:10,244
It's like pinhole cameras and geometric optics.
293
00:24:10,404 --> 00:24:13,482
It's not nearly as fancy as some of the...
294
00:24:13,482 --> 00:24:15,717
diagnostics that are being fielded in other fields.
295
00:24:15,717 --> 00:24:17,902
But that's largely because it can't be, right?
296
00:24:17,902 --> 00:24:25,256
It's very hard to have X-ray optics in a compact space because X-rays don't really refract
the way that visible light does.
297
00:24:27,286 --> 00:24:30,419
Damn, yeah.
298
00:24:30,419 --> 00:24:34,381
This is fascinating.
299
00:24:35,042 --> 00:24:46,562
So maybe first, can you walk us through the main technical or methodological obstacles you
face just even before starting to analyze and model this data?
300
00:24:46,562 --> 00:24:54,959
Like, what's the first step in your workflow when you're working on one of the concrete
projects you've named at the beginning of the show?
301
00:24:54,959 --> 00:24:55,299
Sure.
302
00:24:55,299 --> 00:24:56,944
So the first step.
303
00:24:56,944 --> 00:25:03,430
is designing these large scale experiments to be done on these football field size lasers.
304
00:25:03,430 --> 00:25:09,415
And so that work usually starts about a little more than a year out.
305
00:25:09,415 --> 00:25:15,981
You propose an experiment, it gets accepted or rejected or iterated on by the committee.
306
00:25:16,221 --> 00:25:18,724
You get time on the laser, you get usually one day.
307
00:25:18,724 --> 00:25:23,680
ah And so then your day is scheduled for the next fiscal year and you have to
308
00:25:23,680 --> 00:25:24,650
design your experiment.
309
00:25:24,650 --> 00:25:27,481
So you got to say, all right, what's my target going to look like?
310
00:25:27,481 --> 00:25:29,061
How it's the laser pulse going to look like?
311
00:25:29,061 --> 00:25:30,842
How much energy do I want?
312
00:25:31,262 --> 00:25:34,023
What am I looking to actually observe here?
313
00:25:34,023 --> 00:25:37,684
And what measurement is going to give me the most information?
314
00:25:37,804 --> 00:25:40,724
And so that requires a lot of simulations.
315
00:25:40,985 --> 00:25:49,577
So we run these very advanced state of the art uh radiation hydrodynamics codes to sort of
predict how the system is going to behave.
316
00:25:49,577 --> 00:25:53,908
It's never right because these systems are really complicated.
317
00:25:54,024 --> 00:25:59,269
And so the codes can never quite capture what's going to happen, but we can get an idea.
318
00:25:59,269 --> 00:26:04,293
uh And then a piece I've really been pushing is trying to do it predictively.
319
00:26:04,293 --> 00:26:16,024
So sort of as a byproduct of this whole Bayesian inference generative modeling, you have
to have a full forward model of your detector.
320
00:26:16,024 --> 00:26:21,169
So that lets you then input your hydrodynamic simulation, for example.
321
00:26:21,169 --> 00:26:23,930
and predict what exact signal am I going to observe?
322
00:26:23,930 --> 00:26:26,171
it, you know, am I going to saturate my camera?
323
00:26:26,171 --> 00:26:30,312
Am I going to be able to resolve the signature, the spectral signature that I want?
324
00:26:30,373 --> 00:26:37,162
And so it involves iterating, you know, at that level to try and simulate your data and
say, this is what I'm going to see.
325
00:26:37,162 --> 00:26:38,275
This is what I think I'm going to see.
326
00:26:38,275 --> 00:26:41,497
ah And then you do the experiment.
327
00:26:41,497 --> 00:26:42,543
It's completely different.
328
00:26:42,543 --> 00:26:45,238
And you're like, well, that's not what I thought was going to happen.
329
00:26:45,318 --> 00:26:50,820
And then you have to start trying to interpret that data, figure out why, what's wrong,
what the simulation got wrong.
330
00:26:50,972 --> 00:27:04,358
and then try and build a better model that's able to capture the data and sort of model
from, you know, physical principles, build a physical model of the system to model this
331
00:27:04,358 --> 00:27:07,299
data and interpret it and try and extract the most information out.
332
00:27:07,299 --> 00:27:16,753
So the technical challenge of designing the experiment is in its own right, you know, a
challenge because doing large-scale science is challenging.
333
00:27:16,753 --> 00:27:20,284
It requires coordinating with a large team of people and
334
00:27:20,284 --> 00:27:27,550
doing a lot of very tedious paperwork to make sure that you can feel the experiment you
want to feel.
335
00:27:28,171 --> 00:27:31,814
And then after that, the data is incredibly complicated.
336
00:27:31,814 --> 00:27:46,827
think, um you know, JJ famously uh only ever uh published data from one shot from his
entire graduate career because these experiments are very difficult to do and then even
337
00:27:46,827 --> 00:27:48,388
more difficult to analyze.
338
00:27:48,451 --> 00:27:57,913
And so it's considered a very, successful uh PhD thesis if you can analyze at least one
data set.
339
00:27:58,194 --> 00:28:09,326
And so being able to extend that and do it for multiple data sets is something that's even
more challenging, even once you've built up the tools, because each individual shot of the
340
00:28:09,326 --> 00:28:11,727
laser is slightly different.
341
00:28:11,727 --> 00:28:15,978
And the nuance of that is something that is...
342
00:28:16,294 --> 00:28:17,845
Because anything can happen.
343
00:28:17,845 --> 00:28:20,577
You can always have some fluke occurrence.
344
00:28:20,577 --> 00:28:31,063
There's sort of an old apocryphal tale that someone was, someone had an experiment on the
laser and a squirrel chewed through a cable on the roof and the whole thing just shut off.
345
00:28:31,063 --> 00:28:32,884
And for the, you know, that was it.
346
00:28:32,884 --> 00:28:36,075
They didn't get any data because the squirrel chewed through a cable on the roof.
347
00:28:36,075 --> 00:28:37,787
It's like, well, couldn't have predicted that.
348
00:28:37,787 --> 00:28:44,310
The code did not, uh did not contain the necessary squirrel physics um to predict that
outcome.
349
00:28:44,588 --> 00:28:46,819
And so any, any number of things can go wrong.
350
00:28:46,819 --> 00:28:59,794
Um, but being able to, to build a robust model and statistical inference engine to
interpret these data sets and get meaningful information out, uh, is, that's, I would say
351
00:28:59,794 --> 00:29:04,536
that's the largest, um, sort of technical challenge.
352
00:29:04,536 --> 00:29:10,949
two, these are, I mean, they're, they're, there's a lot of data, but it's also not a lot
of data by modern standards, right?
353
00:29:10,949 --> 00:29:14,406
We can shoot the laser maybe one, you know,
354
00:29:14,406 --> 00:29:19,089
12 times in a single day, which is a lot for a laser that size.
355
00:29:19,310 --> 00:29:23,793
But you maybe get eight shots of usable data.
356
00:29:23,793 --> 00:29:31,618
And so it's very hard to scan through parameter space and answer the questions that you
might want to answer.
357
00:29:31,979 --> 00:29:37,663
So it's a very complicated and difficult uh paradigm to operate in.
358
00:29:37,663 --> 00:29:40,764
But it's very fun and rewarding as well.
359
00:29:40,805 --> 00:29:41,665
Yeah.
360
00:29:41,926 --> 00:29:42,758
Yeah, again, guys.
361
00:29:42,758 --> 00:29:48,458
Uh, and how does, what's the timeline, you know, on these projects you're working on?
362
00:29:48,458 --> 00:29:55,918
Like for how long does it tend to, like, what's a range of duration you guys are working
on these, on these projects?
363
00:29:55,918 --> 00:30:01,378
Because it sounds so daunting that like, I'm guessing you need a lot of time.
364
00:30:01,378 --> 00:30:01,578
Yeah.
365
00:30:01,578 --> 00:30:09,292
Well, I mean, the timeline for an experiment as you know, as I said, a little over a year,
but then to actually analyze that, I mean, we're talking.
366
00:30:09,292 --> 00:30:10,903
the length of a PhD thesis, right?
367
00:30:10,903 --> 00:30:13,274
JJ analyzed one shot in his thesis.
368
00:30:13,274 --> 00:30:16,516
I'm going to analyze slightly more than one shot, but not by much.
369
00:30:16,516 --> 00:30:23,639
uh It takes, yeah, I would say it takes about five years to finish one of these projects.
370
00:30:23,639 --> 00:30:28,782
uh And a lot of that is because, you know, I'm a graduate student, I'm learning.
371
00:30:29,002 --> 00:30:34,625
There's a lot I didn't know, I didn't know when I started that I know that I don't know
now.
372
00:30:34,625 --> 00:30:38,283
ah And so that definitely makes it
373
00:30:38,283 --> 00:30:39,683
hard to get going at the beginning.
374
00:30:39,683 --> 00:30:49,326
uh But when you're starting from scratch, right, you don't have any of the uh tools
necessarily built out yet.
375
00:30:49,326 --> 00:30:51,427
It's very difficult to get going.
376
00:30:51,427 --> 00:31:02,690
so, you know, that's sort of, hopefully the, you know, I've built up enough tools that
the, you know, my successor, whoever they may be, will be able to build on that just as I
377
00:31:02,690 --> 00:31:06,371
built on what JJ did and, he built on what came before him.
378
00:31:06,471 --> 00:31:07,395
And so.
379
00:31:07,395 --> 00:31:13,675
Hopefully it accelerates, it is very challenging to be able to build out these tools.
380
00:31:14,015 --> 00:31:21,455
Plus, I'm guessing a lot of people are working on these projects, Physics projects are
usually very collaborative.
381
00:31:21,455 --> 00:31:23,135
So how does that look like for you?
382
00:31:23,135 --> 00:31:25,595
How many people are working with you on these projects?
383
00:31:25,595 --> 00:31:31,155
Maybe it's even inter-country collaborations.
384
00:31:31,275 --> 00:31:35,227
I think it's very interesting to also look a bit at that and...
385
00:31:35,393 --> 00:31:46,770
how it looks backstage because not a lot of projects are as high, as large scale and
international as physics projects.
386
00:31:46,951 --> 00:31:48,752
Yeah, that's a good point.
387
00:31:48,752 --> 00:31:54,866
So one thing that's kind of unusual about the field of high-end density physics is it is
very collaborative.
388
00:31:54,866 --> 00:31:57,878
We collaborate uh all over the world.
389
00:31:58,359 --> 00:32:05,513
There's laser systems that we go use all around the world in Europe, Japan, all over.
390
00:32:05,699 --> 00:32:14,359
Um, and so there is that collaboration, but at the same time, it's small enough scale that
you sort of own your project.
391
00:32:14,359 --> 00:32:14,819
Right.
392
00:32:14,819 --> 00:32:16,639
So I proposed my experiments.
393
00:32:16,639 --> 00:32:19,279
had a lot of help fielding that experiment, right.
394
00:32:19,279 --> 00:32:22,379
From a, you know, diagnostic and laser side, right.
395
00:32:22,379 --> 00:32:24,619
I don't know anything about laser systems.
396
00:32:24,619 --> 00:32:29,359
Uh, so there's a whole team of laser professionals at the lab who run the laser.
397
00:32:29,419 --> 00:32:35,639
Um, and so, you know, there's a lot of help from them, but at the end of the day, you
know, I designed it as, as a graduate student, I.
398
00:32:35,639 --> 00:32:41,504
Designed the target, what the laser is going to look like, what diagnostics we're going to
field, and then I'm in charge of analyzing it.
399
00:32:41,504 --> 00:32:49,571
And so it's very collaborative in the sense that everyone works together to get good data,
but you do own your own project at the end of the day.
400
00:32:49,571 --> 00:32:58,177
And there's a lot of freedom that comes with it to pursue what questions you think are
interesting, um, and sort of push the, push the boundaries.
401
00:32:58,458 --> 00:33:03,762
But of course, you know, there's always, um, you can always go talk to experts in the
field.
402
00:33:03,762 --> 00:33:04,923
um
403
00:33:05,089 --> 00:33:08,341
because there is that collaboration, those connections.
404
00:33:08,441 --> 00:33:21,781
But it's definitely not a collaboration in the sense that like CERN or Atlas are where you
have, you know, a hundred people working towards the same uh goal.
405
00:33:21,781 --> 00:33:23,992
It's a lot more individualized.
406
00:33:25,053 --> 00:33:25,393
Yeah.
407
00:33:25,393 --> 00:33:25,694
Okay.
408
00:33:25,694 --> 00:33:26,064
Okay.
409
00:33:26,064 --> 00:33:26,474
I see.
410
00:33:26,474 --> 00:33:30,797
uh And so is there a particular mentor?
411
00:33:33,341 --> 00:33:45,299
that has actually been very important for you so far in your career that has helped you
jumpstart your learning or maybe unblock you on a project?
412
00:33:45,759 --> 00:33:50,622
Yeah, well, I'll definitely shout out JJ Ruby here.
413
00:33:51,183 --> 00:33:54,565
He taught me everything I know about Bayesian inference.
414
00:33:54,565 --> 00:34:02,000
um But then, he went off to go work at Lawrence Livermore and now he's at the Houston
Astros.
415
00:34:02,328 --> 00:34:03,358
but we still, we still talk.
416
00:34:03,358 --> 00:34:10,640
So he's, he's been a huge help in, um, you know, helping me in, cause he was in, he was in
my shoes not long ago.
417
00:34:10,640 --> 00:34:21,823
So he has a lot of, uh, advice, but then, yeah, I, it's been, it's a lot of, um, community
among the graduate students at the lab.
418
00:34:22,284 --> 00:34:25,825
and so I, there's a lot of peer to peer, mentoring.
419
00:34:25,825 --> 00:34:30,346
Um, I'll, I'll shout out David Bischel and Alex Chin.
420
00:34:30,402 --> 00:34:36,667
were two senior graduate students who sort of helped me out when I first came in and knew
absolutely nothing.
421
00:34:36,667 --> 00:34:39,909
And, you know, they sort of taught me what they knew.
422
00:34:39,909 --> 00:34:43,131
ah And now I'm the senior graduate student.
423
00:34:43,131 --> 00:34:48,754
And so I'm trying to pay that forward and, you know, teach me what I learned and what they
taught me.
424
00:34:48,955 --> 00:34:56,500
so there's this sort of, you know, sense of community among graduate students because
we're all sort of in the same boat.
425
00:34:56,840 --> 00:34:58,301
Grad school is hard.
426
00:34:58,341 --> 00:34:59,922
And so it's very...
427
00:35:00,234 --> 00:35:01,436
It's very helpful to have that.
428
00:35:01,436 --> 00:35:06,425
em You have someone you can talk to who's been through this.
429
00:35:06,807 --> 00:35:11,254
So it's not just one mentor, it's a whole lab of them.
430
00:35:13,559 --> 00:35:16,741
Yeah, I can guess that.
431
00:35:16,741 --> 00:35:32,895
And yeah, of course, I will put also JJ's appearance on the show in the show notes for
people who want to dig deeper because JJ definitely has a very interesting background and
432
00:35:32,895 --> 00:35:41,980
path that I think is going to be very valuable for listeners to listen to, especially if
are interested in...
433
00:35:41,980 --> 00:35:45,672
Either physics or baseball analytics or both.
434
00:35:45,672 --> 00:35:48,393
Definitely give a listen to this episode.
435
00:35:48,393 --> 00:35:52,574
And now let's talk a bit more concretely.
436
00:35:52,574 --> 00:35:58,377
How do you incorporate patient inference in your work?
437
00:35:58,377 --> 00:36:05,299
Especially so the kind of high energy density physics uh data you have.
438
00:36:05,440 --> 00:36:11,696
What advantages or limitations arise from using patient techniques?
439
00:36:11,696 --> 00:36:15,867
Yeah, great question and one that people ask me all the time.
440
00:36:15,907 --> 00:36:17,358
They're like, well, what's the point?
441
00:36:17,358 --> 00:36:18,598
Who cares about Bayesian inference?
442
00:36:18,598 --> 00:36:19,908
Why are you doing this?
443
00:36:20,909 --> 00:36:28,391
To which I say Bayesian inference is really the tool that you need to answer a problem
like this.
444
00:36:28,391 --> 00:36:34,372
at a very high level, right, you observe this data and you need to understand the system
that created it.
445
00:36:34,372 --> 00:36:37,453
And so this is a, you know, it's an inverse problem.
446
00:36:37,453 --> 00:36:39,824
And so it's very difficult to just invert the data.
447
00:36:39,824 --> 00:36:41,058
You have to do it.
448
00:36:41,058 --> 00:36:42,999
in a generative framework.
449
00:36:42,999 --> 00:36:46,190
And so right away Bayesian inference is very well suited for that kind of thing.
450
00:36:46,190 --> 00:36:47,491
You don't have to do Bayesian inference.
451
00:36:47,491 --> 00:36:51,763
You can do forward modeling uh without Bayesian statistics.
452
00:36:51,763 --> 00:36:53,894
But it's just such a natural framework for it.
453
00:36:53,894 --> 00:37:02,447
And then on top of that, it allows you ah what I think is probably the most powerful thing
is to include prior information in a way that you can't.
454
00:37:02,447 --> 00:37:06,593
So we have historical data, for example, going back.
455
00:37:06,593 --> 00:37:12,237
several decades to the older version, you know, the, the Omega laser system has been
around since the nineties.
456
00:37:12,478 --> 00:37:16,902
So we have a wealth of historical data that helps us understand these systems.
457
00:37:16,902 --> 00:37:26,930
And so that you can use that as a form of prior knowledge to sort of inform, you know,
your expectations of what's going to come out of what you're going to learn from these
458
00:37:26,930 --> 00:37:28,070
experiments.
459
00:37:28,171 --> 00:37:35,673
And so that, you know, provides a self-consistent way to sort of include that prior
knowledge that will, you know,
460
00:37:35,673 --> 00:37:41,293
improve the statistical inference that you're able to make from these.
461
00:37:41,293 --> 00:37:47,533
Because you can take a lot of measurements, but they're not, they may not have as much
information as you need them to have.
462
00:37:47,533 --> 00:37:51,553
And so being able to impose prior knowledge is also very valuable.
463
00:37:51,973 --> 00:38:03,473
And then also, you know, one thing we struggle with in our field is propagation of
uncertainties, because you have very highly nonlinear systems.
464
00:38:03,605 --> 00:38:15,350
And sometimes you can't uh build a model that's able to uh sort of characterize your level
of uncertainty and Bayesian inference folds that in completely self-consistently and
465
00:38:15,350 --> 00:38:16,597
correlations and whatnot.
466
00:38:16,597 --> 00:38:25,605
you're doing uh Markov chain Monte Carlo, and even if you're doing something like
stochastic variational inference, you can still get a much better understanding of the
467
00:38:25,605 --> 00:38:30,199
uncertainty uh in your system based on your data, which is
468
00:38:30,617 --> 00:38:31,868
very non-trivial for these systems.
469
00:38:31,868 --> 00:38:39,142
So I would say that's the big three uh reasons why we use Bayesian inference to analyze
the data.
470
00:38:39,142 --> 00:38:41,723
It's because I think it just makes sense.
471
00:38:41,743 --> 00:38:51,589
Yeah, mean, preaching to the choir, but yeah, completely relate, of course.
472
00:38:51,589 --> 00:38:59,243
And actually, can you describe one experiment or project that
473
00:38:59,531 --> 00:39:12,546
you're particularly proud of where you used Bayesian inference, um what you measured, how,
why it's significant and what does the model look like?
474
00:39:13,187 --> 00:39:14,328
Yeah, sure.
475
00:39:14,328 --> 00:39:17,019
Well, it's still ongoing, so it's not done.
476
00:39:17,019 --> 00:39:21,651
I don't know if I'm allowed to be proud of it if uh it hasn't been published yet, but
that's fine.
477
00:39:21,651 --> 00:39:25,152
um So one thing that...
478
00:39:25,152 --> 00:39:27,095
um
479
00:39:27,095 --> 00:39:40,197
This sort of the what's become my main project at this point is uh making a sort of
measurement of the equation of state of a billion atmosphere pressure plasma.
480
00:39:40,318 --> 00:39:44,922
So the equation of state is just the relationship between pressure, temperature, intensity
basically.
481
00:39:44,922 --> 00:39:51,065
You think of the ideal gas law, uh van der Waals equation of state maybe to name a few.
482
00:39:51,065 --> 00:39:52,122
And so
483
00:39:52,122 --> 00:39:54,233
It's a very important material property, right?
484
00:39:54,233 --> 00:40:00,066
Because it says, if you're at a temperature and density, what's the pressure, what's the
energy density, and so forth.
485
00:40:00,326 --> 00:40:07,440
And so we've sort of developed the tools to do this at lower pressures, uh fairly
routinely.
486
00:40:07,440 --> 00:40:12,273
You can measure the temperature, density, and pressure of a planar experiment, for
example.
487
00:40:12,273 --> 00:40:17,665
So you can get all the very high pressure, but you can't, as I said, there's a limit to
how hard you can hit something with a laser.
488
00:40:17,665 --> 00:40:21,197
So you can't measure the equation of state beyond
489
00:40:21,235 --> 00:40:24,287
you know, 10 million atmospheres or so.
490
00:40:24,768 --> 00:40:29,773
And so, you know, you have to go to a convergent geometry, but that's very difficult.
491
00:40:29,773 --> 00:40:41,613
And so, um sort of what's become my mission is making that measurement using Bayesian uh
inference techniques and other statistical methods, know, machine learning and whatnot, to
492
00:40:41,613 --> 00:40:47,899
take this really, this big data set um that, you know, consists of
493
00:40:47,899 --> 00:40:59,467
multiple different X-ray cameras, spectrometers, all sorts of, you know, the full kitchen
sink and analyzing that data set, this multi-messenger data set, uh comprehensively at the
494
00:40:59,467 --> 00:41:05,131
same time and sort of in the data space as much as possible.
495
00:41:05,131 --> 00:41:07,983
So sort of from first principles, if you will.
496
00:41:08,423 --> 00:41:14,338
And so, you know, this was a really complicated system just to build, right?
497
00:41:14,338 --> 00:41:16,749
You have to build models of all these detectors.
498
00:41:16,775 --> 00:41:30,819
and understand the statistics uh in some sense, and then do the inference, which is going
to be a very high dimensional problem um requiring the very advanced sampling tools
499
00:41:30,819 --> 00:41:34,742
provided by PyMC and other libraries.
500
00:41:35,263 --> 00:41:41,509
And so what we were able to do is take that data set and
501
00:41:41,509 --> 00:41:45,762
throw this very complicated model at it, which is it's complicated, but it's simple,
right?
502
00:41:45,762 --> 00:41:54,739
Because it's basically, you know, you have your temperature and you have your density and
your pressure, and you have a very simple, but sort of complete physical picture of how
503
00:41:54,739 --> 00:42:06,047
they evolve in time and space that's sort of parameterized in terms of these physical
quantities, but flexible enough to be able to fit the data while encoding, you know, our
504
00:42:06,047 --> 00:42:08,745
prior belief on the physics of the system.
505
00:42:08,745 --> 00:42:12,566
Like for example, you we think the temperature should go up and then down, right?
506
00:42:12,786 --> 00:42:15,027
And then stuff like that.
507
00:42:15,227 --> 00:42:24,119
And so doing that, building this model that, you know, treats the evolution of the system
and then, you know, propagates that forward.
508
00:42:24,119 --> 00:42:25,620
What X-rays does that produce?
509
00:42:25,620 --> 00:42:27,010
How do we observe those?
510
00:42:27,010 --> 00:42:28,650
What would we measure if that were the case?
511
00:42:28,650 --> 00:42:33,172
Bayesian inference, you know, the likelihood of uh data given theta.
512
00:42:33,432 --> 00:42:38,005
And then we are able to sort of independently constrain the
513
00:42:38,005 --> 00:42:42,068
pressure, temperature, and density from the available suite of measurements.
514
00:42:42,068 --> 00:42:46,353
And so that gives you sort of separate measurements of what's the temperature and density
and what's the pressure.
515
00:42:46,353 --> 00:42:49,435
And those are related by the equation of state.
516
00:42:49,836 --> 00:42:56,703
And so this gives you a very fancy way to measure the equation of state using these
advanced statistical methods.
517
00:42:56,703 --> 00:43:03,018
And so we were able to do that for the first time, and that gives you sort of insight into
what physics is happening, right?
518
00:43:03,018 --> 00:43:04,117
You can sort of...
519
00:43:04,117 --> 00:43:06,258
You can compare it to your models.
520
00:43:06,258 --> 00:43:12,170
can do further inference on those conditions that you infer and try and understand what's
happening here.
521
00:43:12,170 --> 00:43:17,704
there sort of interactions that we aren't taking into account in the physics of the
system?
522
00:43:17,844 --> 00:43:20,326
Is it just the ideal gas law?
523
00:43:20,326 --> 00:43:21,797
Is there something else going on?
524
00:43:21,797 --> 00:43:26,429
uh Are the photons that we're creating producing their own pressure?
525
00:43:26,729 --> 00:43:28,830
Let's ask a lot of interesting questions.
526
00:43:29,851 --> 00:43:32,912
to my knowledge, it's the first measurement uh out there.
527
00:43:32,912 --> 00:43:34,253
uh
528
00:43:34,321 --> 00:43:36,322
these billion atmosphere pressures.
529
00:43:36,982 --> 00:43:49,329
And so, you we're still working on uh putting that together for publication, but just, you
know, the sheer lift of putting it together and doing it in a self-consistent way is
530
00:43:49,329 --> 00:43:59,774
something that I'm proud of and has really, you know, pushed uh what JJ did with his
single diagnostic, single shot analysis to a, you know, a more complete framework.
531
00:43:59,774 --> 00:44:03,992
And then, you know, because I took multiple shots of data,
532
00:44:03,992 --> 00:44:06,894
I can, I think I've analyzed seven, seven shots now.
533
00:44:06,894 --> 00:44:16,562
Uh, so that's, you know, a vast improvement for, for the statistics, know, square root of
N was so much more, uh, so much more certain.
534
00:44:16,943 --> 00:44:17,293
Yeah.
535
00:44:17,293 --> 00:44:17,608
Yeah.
536
00:44:17,608 --> 00:44:17,924
Yeah.
537
00:44:17,924 --> 00:44:18,224
Damn.
538
00:44:18,224 --> 00:44:18,945
Well done.
539
00:44:18,945 --> 00:44:26,351
Um, yeah, I know this is, this is such a, such a hard work, but very impressive.
540
00:44:26,351 --> 00:44:31,576
And how, so first practical question, because I'm always curious.
541
00:44:31,576 --> 00:44:32,586
What?
542
00:44:32,716 --> 00:44:36,777
What did you use to code the actual model and to sample?
543
00:44:36,777 --> 00:44:39,838
Did you use any already existing package?
544
00:44:39,838 --> 00:44:46,980
um Did you have to come up with your custom packages, maybe even custom sample?
545
00:44:46,980 --> 00:44:48,301
How does it work?
546
00:44:48,301 --> 00:44:49,821
What does it look like?
547
00:44:49,821 --> 00:44:57,604
So I am a big proponent of Python, doing everything in Python, which is uh an increasingly
popular opinion, out.
548
00:44:57,604 --> 00:44:57,904
Python...
549
00:44:57,904 --> 00:44:58,990
uh
550
00:44:58,990 --> 00:45:04,564
When I first started, no one in my lab was using Python, which was crazy, except for JJ.
551
00:45:04,564 --> 00:45:08,727
It was, everyone is using like Matlab, Excel, Mathematica.
552
00:45:08,727 --> 00:45:09,888
Python was...
553
00:45:09,888 --> 00:45:12,629
Damn, this is A lot of people still use Excel.
554
00:45:12,629 --> 00:45:18,073
I will say, you in their defense, what they're able to do with Excel is nothing short of
magic.
555
00:45:18,073 --> 00:45:18,283
mean...
556
00:45:18,283 --> 00:45:18,834
Yeah, yeah.
557
00:45:18,834 --> 00:45:22,536
I mean, at that level, you have to be an Excel...
558
00:45:22,536 --> 00:45:25,548
I mean, they're doing everything I can do in Python.
559
00:45:25,548 --> 00:45:26,639
They are doing an Excel.
560
00:45:26,639 --> 00:45:28,780
It just looks ridiculous.
561
00:45:29,413 --> 00:45:29,693
Yeah.
562
00:45:29,693 --> 00:45:30,233
Yeah.
563
00:45:30,233 --> 00:45:30,853
Damn.
564
00:45:30,853 --> 00:45:31,554
Wow.
565
00:45:31,554 --> 00:45:32,255
Okay.
566
00:45:32,255 --> 00:45:33,866
Um, but good choice.
567
00:45:33,866 --> 00:45:40,042
I, I, I completely support you, Ethan and JJ, this, this endeavor.
568
00:45:40,042 --> 00:45:48,109
uh, yeah, so, so we're big, big, uh, proponents of Python and the sort of big knock on
Python is that it's slow.
569
00:45:48,479 --> 00:45:56,336
but that's actually becoming less and less of an issue when you have things like, you
know, just in time compilation, uh with, Jack's.
570
00:45:56,852 --> 00:46:00,815
and other things that are, you automatic differentiation.
571
00:46:00,815 --> 00:46:08,301
All of that is sort of closing the gap between Python and these sort of machine, you know,
Fortran and C++ and whatnot.
572
00:46:08,301 --> 00:46:18,970
And so the ease of use is so much better that, you know, coding in Python is really,
think, I mean, you obviously agree, is the practical choice at this stage.
573
00:46:18,970 --> 00:46:21,656
uh And so, you know,
574
00:46:21,656 --> 00:46:23,518
A lot of it is pre-existing, right?
575
00:46:23,518 --> 00:46:25,500
There's the Jax libraries.
576
00:46:25,500 --> 00:46:27,381
A lot of code exists.
577
00:46:27,381 --> 00:46:32,225
I didn't have to recode NP.traps or anything like that.
578
00:46:32,446 --> 00:46:37,770
But there's a lot of very bespoke code that I had to rewrite in Jax.
579
00:46:37,770 --> 00:46:42,894
That's an implementation that doesn't exist that does exactly what I want it to do.
580
00:46:43,095 --> 00:46:48,918
so I had to do a lot of software development uh considering I...
581
00:46:48,918 --> 00:46:55,511
came into college or uh graduate school rather with zero, basically zero Python
experience.
582
00:46:55,511 --> 00:47:04,874
And so I had to teach myself from the ground up uh how to code in Python and then how to
code in Jax and then how to develop a large scale software package.
583
00:47:04,874 --> 00:47:09,836
ah It's not beautiful, but it does work.
584
00:47:09,836 --> 00:47:17,439
that's another thing that I guess I should add that I'm proud of is the sheer amount of
code that I've written.
585
00:47:17,483 --> 00:47:18,774
uh for this project.
586
00:47:18,774 --> 00:47:20,465
It's a massive repository.
587
00:47:20,465 --> 00:47:24,237
uh Just to, you know, analyze a couple pieces of data.
588
00:47:24,237 --> 00:47:28,729
yeah, shout out to Python, shout out to Jax.
589
00:47:28,729 --> 00:47:35,753
um We used to use PyMC as our sampling library to do the inference.
590
00:47:35,874 --> 00:47:45,939
We switched recently to NumPyro because that was, you know, this is when NumPyro was sort
of new and Jax was sort of cutting edge.
591
00:47:46,175 --> 00:47:49,896
And now think PyMC uses Jax at its backend.
592
00:47:50,156 --> 00:47:51,876
Yeah, I mean, you can.
593
00:47:52,877 --> 00:47:55,758
Yeah, we have the three backends.
594
00:47:55,758 --> 00:47:58,878
So C is the default one.
595
00:47:58,999 --> 00:48:01,049
You can use Numba and you can use Jax.
596
00:48:01,049 --> 00:48:08,081
So depending on the project you're working on, be useful to use Numba or it will be faster
using Jax.
597
00:48:08,081 --> 00:48:10,462
It depends on your model.
598
00:48:10,882 --> 00:48:13,583
yeah, that's great.
599
00:48:14,565 --> 00:48:22,561
Anyway, you're using a very good open source package and you build on top of um it.
600
00:48:22,561 --> 00:48:24,762
What are you using as a sampler?
601
00:48:26,564 --> 00:48:28,585
latest MCMC?
602
00:48:29,286 --> 00:48:31,347
So yeah, it depends.
603
00:48:31,347 --> 00:48:35,850
eh Usually we use, know, not Snowy U-turn sampler.
604
00:48:35,850 --> 00:48:42,921
um I mean, have to sort of coax it to do what you want on occasion, but it's...
605
00:48:42,921 --> 00:48:47,333
sort of the Ferrari of samplers, as far as we're concerned.
606
00:48:48,153 --> 00:48:56,517
Occasionally, they will, you when you drive a Ferrari on a road full of potholes, you will
occasionally encounter a negative result.
607
00:48:56,597 --> 00:49:03,881
And so we may have to use, you know, something like sequential Monte Carlo SMC or some
other more robust but slower.
608
00:49:03,881 --> 00:49:08,362
uh Nest and sampling is another one that I've used a lot.
609
00:49:09,675 --> 00:49:15,555
So it's unfortunate because you'd like there to be one sampler that always works, but that
is never the case.
610
00:49:15,555 --> 00:49:18,255
And you always have to do something else.
611
00:49:18,715 --> 00:49:25,754
Sometimes when you get really desperate, you'll be like, all right, we've got to use a
totally different sampling library to get what we want.
612
00:49:25,754 --> 00:49:27,815
But that's part of the and part of the fun.
613
00:49:27,815 --> 00:49:34,835
It's already working for most of the, like for 98 % of the cases, and since it will be
amazing.
614
00:49:34,835 --> 00:49:37,715
I mean, that's, and so, yeah.
615
00:49:37,993 --> 00:49:41,796
And that's great to hear that you didn't have to code your custom sampler.
616
00:49:41,796 --> 00:49:42,106
Right.
617
00:49:42,106 --> 00:49:48,071
So you see folks, you don't need to, you don't need to write your custom samplers anymore.
618
00:49:48,071 --> 00:49:54,216
Especially I'm, I'm, I'm speaking to the economics, uh, among econometricians among us.
619
00:49:54,216 --> 00:49:57,719
Like don't stop writing your own custom gift sampler.
620
00:49:58,280 --> 00:50:06,746
Just, uh, just use the ones that are in PIMC or NumPyro or Stan or whatever you're using
as a probabilistic programming language is going to work well.
621
00:50:06,746 --> 00:50:07,898
And there are now.
622
00:50:07,898 --> 00:50:11,190
More than the nut sampler, there are many more of them.
623
00:50:11,190 --> 00:50:12,671
I % agree.
624
00:50:13,012 --> 00:50:19,156
And I've been trying to proselytize a little bit around different research groups.
625
00:50:19,156 --> 00:50:31,594
I've got some Bayesian inference outreach uh presentations that I've been giving, trying
to spread the word that, hey, Bayesian inference is not as hard as it used to be in the
626
00:50:31,594 --> 00:50:32,124
olden days.
627
00:50:32,124 --> 00:50:33,505
You don't have to write your own sampler.
628
00:50:33,505 --> 00:50:36,647
You can just use one of these excellent uh
629
00:50:36,647 --> 00:50:40,928
pre-made ones that are only getting better and more sophisticated.
630
00:50:41,108 --> 00:50:41,868
exactly.
631
00:50:41,868 --> 00:50:44,909
The barrier to entry is so much lower now.
632
00:50:44,909 --> 00:50:45,489
Exactly.
633
00:50:45,489 --> 00:50:46,740
It's way, way lower.
634
00:50:46,740 --> 00:51:03,185
So now you can spin up a patient model and sample from it very fast and don't even have to
worry about the sampling issues because it's all taken care of for you.
635
00:51:03,185 --> 00:51:04,995
I would say it's
636
00:51:05,575 --> 00:51:07,056
It's a great time to leave.
637
00:51:07,056 --> 00:51:16,863
m And a lot of people are scared of Bayesian inference because it sounds fancy, but it's,
know, really, you know, quite easy.
638
00:51:16,863 --> 00:51:22,266
just build your model, turn the crank, Bayes rule and get out your posterior.
639
00:51:22,346 --> 00:51:24,267
Yeah, exactly.
640
00:51:25,148 --> 00:51:26,539
Not a lot of things to do now.
641
00:51:26,539 --> 00:51:29,501
It's pretty much, pretty much all automated.
642
00:51:29,501 --> 00:51:30,162
It's solved.
643
00:51:30,162 --> 00:51:30,652
Yeah.
644
00:51:30,652 --> 00:51:33,233
Bayesian inference is it's all done.
645
00:51:34,154 --> 00:51:35,075
Yeah.
646
00:51:35,353 --> 00:51:46,703
Actually, do you have um any good practices that you want to share with people when
they're working with big code bases as you are?
647
00:51:46,703 --> 00:51:50,749
um Well, in your case in Python, but can be, can be anything else?
648
00:51:50,749 --> 00:52:04,375
Like what are, what are the good practices you've found to not lose yourself basically
when working on these, on these big code bases and also probably to help.
649
00:52:04,551 --> 00:52:07,953
uh collaboration as we were talking about.
650
00:52:08,134 --> 00:52:10,915
Well, the first thing is always comment your code.
651
00:52:10,915 --> 00:52:22,363
And I say this with full knowledge that I am not very good at this, but always, for your
future self at the very least, you know, write down your thought process so you can come
652
00:52:22,363 --> 00:52:23,324
back to it.
653
00:52:23,744 --> 00:52:33,611
But then on a, you know, sort of more sophisticated level, uh there's a sort of white
paper by Andrew Goman.
654
00:52:33,707 --> 00:52:40,993
I think it's called a principal Bayesian workflow that sort of lays out best practices for
constructing a model.
655
00:52:40,993 --> 00:52:47,098
And so, you construct your model, you uh test the prior predictive distribution.
656
00:52:47,098 --> 00:52:49,150
You you say, okay, is my prior correct?
657
00:52:49,150 --> 00:52:50,600
And then you go.
658
00:52:50,681 --> 00:53:02,330
And I think one thing that's really useful, especially in, you know, the sort of work that
I do is building a sort of synthetic experiment and, you know, making sure that you can
659
00:53:02,330 --> 00:53:03,131
get out
660
00:53:03,131 --> 00:53:05,022
the information you think you can get out, right?
661
00:53:05,022 --> 00:53:15,369
Because if you build this whole synthetic set of synthetic diagnostics and your model, and
then you take the data and you try to analyze it and you actually don't get any
662
00:53:15,369 --> 00:53:16,400
information out.
663
00:53:16,400 --> 00:53:17,621
Well, great.
664
00:53:17,621 --> 00:53:22,905
You you wasted a bunch of time and money on that experiment and you didn't get what you
wanted out.
665
00:53:22,905 --> 00:53:31,891
And so being able to sort of, before you've even done the experiment, predict what you're,
what you're going to measure and then what information you can get out of that is hugely
666
00:53:31,891 --> 00:53:32,761
helpful.
667
00:53:33,023 --> 00:53:40,306
And really, you know, should be a prerequisite for doing any of these experiments and
showing that you think it's going to work.
668
00:53:40,306 --> 00:53:49,239
I mean, there's value in just shooting a laser and seeing what happens, but at this stage,
you know, the field is advanced enough that we should be doing this a little more
669
00:53:49,239 --> 00:53:50,510
predictively.
670
00:53:51,210 --> 00:53:56,312
And then two, sort of um benchmarking and testing your model along the way.
671
00:53:56,312 --> 00:54:01,652
And so one thing that I really struggled with is I sort of put the model together all at
once.
672
00:54:01,652 --> 00:54:03,744
And I just pressed go and it didn't work.
673
00:54:03,744 --> 00:54:06,125
And I was like, well, what, why didn't it work?
674
00:54:06,166 --> 00:54:06,896
What's breaking?
675
00:54:06,896 --> 00:54:09,188
And so then I was like, well, okay.
676
00:54:09,188 --> 00:54:15,314
I took it apart and piece by piece, you know, and I tested each module, made sure it did
what I thought it was doing.
677
00:54:15,314 --> 00:54:20,728
You know, ran the inference, you know, ran the synthetic experiment, but let's say, okay,
let's say there's no noise.
678
00:54:20,728 --> 00:54:22,079
It's a perfect measurement.
679
00:54:22,079 --> 00:54:23,540
Can I, does this work?
680
00:54:23,540 --> 00:54:30,676
so building confidence in your model is very important and convincing yourself that it
works so that you can convince others.
681
00:54:31,262 --> 00:54:33,543
And that helps you find a lot of the issues.
682
00:54:33,744 --> 00:54:39,327
Because you definitely can lose yourself ah in the model building process.
683
00:54:39,327 --> 00:54:43,879
As fun as it is, ah once the model gets too big, there's nothing you can do.
684
00:54:43,879 --> 00:54:44,769
gotta...
685
00:54:45,070 --> 00:54:46,851
You gotta just, you know, one brick at a time.
686
00:54:46,851 --> 00:54:52,213
And after you place each brick, make sure that that brick is a brick.
687
00:54:52,734 --> 00:54:53,594
Hmm.
688
00:54:54,315 --> 00:54:55,856
Yeah, yeah, okay.
689
00:54:55,856 --> 00:54:57,136
Yeah, I see what you mean.
690
00:54:57,136 --> 00:54:58,737
So basically...
691
00:54:59,638 --> 00:55:00,658
Having...
692
00:55:01,076 --> 00:55:07,630
A principled patient workflow, building block by block and testing it along the way.
693
00:55:07,630 --> 00:55:08,530
Is that correct?
694
00:55:08,530 --> 00:55:12,822
So how do you benchmark and test your model actually?
695
00:55:12,822 --> 00:55:18,916
How do you, what does a good model look like to you in this kind of project?
696
00:55:18,916 --> 00:55:21,217
How do you call a model good?
697
00:55:21,217 --> 00:55:22,282
How do you evaluate it?
698
00:55:22,282 --> 00:55:23,448
How do you benchmark it?
699
00:55:23,448 --> 00:55:30,338
I think it's a very important question, not only in your case, but in everybody's case,
like all my models, I need to benchmark them.
700
00:55:30,338 --> 00:55:37,201
So yeah, I'm curious, what does that look like for you and what does that mean to have a
good model?
701
00:55:37,382 --> 00:55:37,982
Right.
702
00:55:37,982 --> 00:55:45,796
So for me, for the specific use case that I work on, a good, well, all models are wrong,
but some models are useful.
703
00:55:45,796 --> 00:55:51,309
So a good model is one that is useful that you can use to get useful information about
your system out.
704
00:55:51,330 --> 00:55:59,906
And so what that usually looks like is we'll run a, you know, state of the art, a full
physics simulation, you know, hydrodynamics code.
705
00:55:59,906 --> 00:56:10,826
simulate our experiment, generate synthetic data from that using our state-of-the-art
detector models, and then do inference on that synthetic data and say, okay, so we know
706
00:56:10,826 --> 00:56:14,986
what the ground truth value is from our simulation.
707
00:56:14,986 --> 00:56:17,726
Can we recover that with our model?
708
00:56:17,726 --> 00:56:21,946
And oftentimes the model is a vastly simplified physical model, right?
709
00:56:21,946 --> 00:56:27,746
Because these state-of-the-art simulations take hours to sometimes days to run one
simulation.
710
00:56:27,746 --> 00:56:28,626
So you can't
711
00:56:28,626 --> 00:56:33,787
really iterate over parameter space on that time scale.
712
00:56:33,888 --> 00:56:40,209
And so it's important to do this full physics and benchmark your reduced order model on
that.
713
00:56:40,329 --> 00:56:45,611
And then if that works great, so maybe you benchmarked it against a 1D simulation, it
worked great.
714
00:56:45,611 --> 00:56:49,832
You go up to a 2D simulation or a 3D simulation and see, it still work?
715
00:56:49,832 --> 00:56:51,132
Do we still get useful information?
716
00:56:51,132 --> 00:56:56,680
And so verifying that you can get out of this set of integrated measurements.
717
00:56:56,680 --> 00:56:58,932
Can you recover the ground truth value?
718
00:56:58,932 --> 00:57:01,341
In the limiting case, when you know what it is.
719
00:57:01,341 --> 00:57:07,997
And that builds confidence that the result you get out of the experimental data is
meaningful and useful.
720
00:57:07,998 --> 00:57:14,682
And so that's a very important piece of model development for the specific use case I work
on.
721
00:57:14,682 --> 00:57:21,246
I don't know what that really looks like in other fields where maybe in social sciences
and whatnot.
722
00:57:21,246 --> 00:57:24,268
I don't know if you can simulate an entire economy.
723
00:57:24,268 --> 00:57:25,487
uh
724
00:57:25,487 --> 00:57:27,757
and the stock market, maybe you can.
725
00:57:30,198 --> 00:57:31,699
Yeah, you probably can.
726
00:57:31,699 --> 00:57:39,021
um I think Jesse Grabowski would be able to talk about that, but I know he does a lot of
simulation work.
727
00:57:39,021 --> 00:57:46,343
mean, at some point also it looks a lot like physics simulations when you're simulating a
full economy.
728
00:57:46,343 --> 00:57:51,994
uh There's a lot of interactions and dynamics.
729
00:57:51,994 --> 00:57:55,405
so state space models actually look
730
00:57:55,503 --> 00:58:01,718
Like it look a lot like um physics simulations.
731
00:58:01,798 --> 00:58:05,041
You can definitely use that in physics, I'm sure.
732
00:58:05,053 --> 00:58:10,286
a lot of physicists do go work on Wall Street after their PhDs.
733
00:58:10,286 --> 00:58:12,547
It's either baseball or Wall Street.
734
00:58:12,547 --> 00:58:12,868
Right.
735
00:58:12,868 --> 00:58:13,548
Yeah.
736
00:58:13,548 --> 00:58:17,871
I mean, you can really do anything with physics.
737
00:58:18,112 --> 00:58:21,634
yeah, that's what you could have answered your parents.
738
00:58:21,755 --> 00:58:24,237
Well, you can do anything with a physics degree.
739
00:58:24,349 --> 00:58:26,150
Well, I didn't know that at the time, but I know.
740
00:58:26,150 --> 00:58:27,450
Yeah.
741
00:58:27,450 --> 00:58:30,711
Now you can't, now you can't.
742
00:58:31,132 --> 00:58:41,916
And actually, since you talk about simulations, I know Andrew Gell-Mann, for instance, is
a big proponent of simulating the data and testing the models on simulated data, which I
743
00:58:41,916 --> 00:58:44,558
do all the time also because, you know, I'm a good student.
744
00:58:44,558 --> 00:58:45,938
listen to Andrew.
745
00:58:46,979 --> 00:58:48,429
He knows way better than I do.
746
00:58:48,429 --> 00:58:51,481
How does that look like for you?
747
00:58:51,481 --> 00:58:52,709
You know, how do you...
748
00:58:52,709 --> 00:58:57,012
balance, simulation, modeling, experimenting your own work?
749
00:58:57,052 --> 00:59:06,538
And a bit more generally, which side, if there is one, theory or experiment, do you find
more challenging or more rewarding?
750
00:59:07,399 --> 00:59:13,673
Yeah, well, so I do a fair amount of simulations, right?
751
00:59:13,673 --> 00:59:17,086
I use these large scale physics codes to simulate my experiments.
752
00:59:17,086 --> 00:59:21,018
ah And, you know, as I alluded to earlier, they're sort of always wrong.
753
00:59:21,018 --> 00:59:22,489
They're not predictive.
754
00:59:22,661 --> 00:59:30,769
which is a big problem, ah especially when you start thinking about using implosion
experiments for fusion applications, right?
755
00:59:30,769 --> 00:59:40,718
You want to make more neutrons, and so you want to be able to use your simulations to say,
what do I change to make more yield, more fusions?
756
00:59:40,718 --> 00:59:47,704
ah And so having a code that's not predictive is not particularly useful in that capacity.
757
00:59:47,904 --> 00:59:48,985
And so...
758
00:59:49,255 --> 00:59:57,789
For me, the use of the simulations is that it provides a sort of physically
self-consistent system to test your models on.
759
00:59:58,269 --> 00:59:59,930
It's not correct.
760
00:59:59,930 --> 01:00:12,585
It's not a perfect picture of what's going to happen in your experiment, but it provides a
sort of synthetic ah universe, a self-consistent universe for you to sort of test your
761
01:00:12,585 --> 01:00:13,696
models on.
762
01:00:13,716 --> 01:00:16,477
And so to me, I mean...
763
01:00:16,481 --> 01:00:19,804
I think any experimentalist would tell you that the experiment is king.
764
01:00:19,804 --> 01:00:24,407
Reality, what actually happens is the most important thing.
765
01:00:24,407 --> 01:00:32,913
And the theory should try to be predictive of what actually happens rather than,
oftentimes what happens, you'll do the experiment, it doesn't match your initial
766
01:00:32,913 --> 01:00:33,484
simulation.
767
01:00:33,484 --> 01:00:37,759
And so you'll tune your simulation to sort of match it and you'll add some fudge factors,
whatever.
768
01:00:37,759 --> 01:00:39,248
you're like, look, we discovered this thing.
769
01:00:39,248 --> 01:00:40,759
It's like, wow.
770
01:00:40,759 --> 01:00:43,861
It would have been nice if you could have predicted it beforehand.
771
01:00:44,217 --> 01:00:53,002
uh And so I sort of you know make fun of my theorist colleagues a little bit and could see
know they have these predictions and it's like well It doesn't match doesn't match the
772
01:00:53,002 --> 01:00:57,795
experiment if not, then I don't you know, but then they'll always find that well Maybe
your experiment is wrong.
773
01:00:57,795 --> 01:01:00,056
It's like but you know it happens.
774
01:01:00,056 --> 01:01:07,860
Okay, good this You know, we're all sharing the same experiential reality We all agree
that we did the experiment and this is what happened.
775
01:01:07,860 --> 01:01:12,823
But it's a it's a yeah, it's an interesting uh inner play
776
01:01:12,845 --> 01:01:20,298
because both sides are saying the other one is wrong and that it has to be, we have
quantum accurate density functional theory calculation.
777
01:01:20,298 --> 01:01:22,129
This is the truth.
778
01:01:22,569 --> 01:01:28,752
But every side has its, there are skeletons in everyone's closet.
779
01:01:29,112 --> 01:01:30,912
It's things that we don't understand.
780
01:01:30,913 --> 01:01:41,207
so, ah trying to sort of unify those two silos is an ongoing struggle and something that
we've been trying to work on sort of.
781
01:01:41,207 --> 01:01:49,202
have theorists and experimentalists work together on experimental design, for example, uh
to do an experiment that better answers the outstanding questions.
782
01:01:49,202 --> 01:01:59,409
um But as, you know, in so far as I go, my uh philosophy is always that the theory should
try to be predictive of the experiment.
783
01:01:59,690 --> 01:02:10,077
And if it's not, then it's not a useful simulation outside of this, you know, idea of a
synthetic experiment to benchmark your models.
784
01:02:10,077 --> 01:02:10,873
Yeah, yeah, yeah.
785
01:02:10,873 --> 01:02:13,513
Yeah, yeah, that makes sense.
786
01:02:13,993 --> 01:02:16,873
and yeah, I completely, completely agree with you.
787
01:02:16,873 --> 01:02:18,753
have a way of doing things for sure.
788
01:02:18,753 --> 01:02:20,613
Uh, that's also in my own work.
789
01:02:20,613 --> 01:02:23,513
How, how I do it in the end.
790
01:02:23,893 --> 01:02:28,313
Experiment and autism perpetuation are king.
791
01:02:28,313 --> 01:02:40,777
It's like if, if they don't go well, but the rest is looking good, then I, my, my belief
in the model being an actuate depiction of reality is not.
792
01:02:40,777 --> 01:02:43,798
is definitely decreased by a lot.
793
01:02:43,818 --> 01:03:01,886
And something I am very curious about just to change gears a bit, a bit more general
question, but it seems to me like high energy density physics can be contributing to a lot
794
01:03:01,886 --> 01:03:09,749
of different subfields of physics, uh astrophysics, planetary science, materials research
even under extreme conditions.
795
01:03:09,749 --> 01:03:10,751
uh
796
01:03:10,751 --> 01:03:16,144
How do you see high energy density physics?
797
01:03:16,144 --> 01:03:17,045
It's hard for me.
798
01:03:17,045 --> 01:03:23,049
uh We usually just uh abbreviate it as HED physics, if that's easier.
799
01:03:23,049 --> 01:03:24,319
Okay, HED.
800
01:03:24,319 --> 01:03:26,090
That's going to be easier.
801
01:03:26,090 --> 01:03:35,936
So how do you see HED contributing to the different subfields and what are maybe some
exciting projects that are looking into that currently?
802
01:03:35,936 --> 01:03:37,127
Yeah, absolutely.
803
01:03:37,127 --> 01:03:45,263
So, I I sort of alluded to this earlier, but you're recreating states that exist at the
center of astrophysical objects.
804
01:03:45,563 --> 01:03:50,867
And so it turns astronomy from an observational science to one that you can do in the
laboratory.
805
01:03:50,867 --> 01:04:00,434
ah And so one of the, this is sort of the focus of the Center for Matter Atomic Pressures,
which is an NSF Frontier Center at the University of Rochester.
806
01:04:00,434 --> 01:04:03,336
um So we're, you know,
807
01:04:03,336 --> 01:04:09,882
It's using NSF money to get time on these lasers to study outstanding sort astrophysical
questions.
808
01:04:10,122 --> 01:04:21,212
And sort of one of those uh questions is sort of dealing with the missibility of hydrogen
and helium in these gas giant planets.
809
01:04:21,212 --> 01:04:29,992
So, you we know now from the Juno missions and other space probes that we don't really
understand what's going on inside these gas giants inside Jupiter.
810
01:04:29,992 --> 01:04:32,854
particular, know, is the core, is it a solid core?
811
01:04:32,854 --> 01:04:34,194
Is it dilute?
812
01:04:34,215 --> 01:04:38,096
Turns out it's somewhere in the middle, where it's the sort of fuzzy core.
813
01:04:38,197 --> 01:04:43,640
And that sort of flies in the face of everything we thought we knew about planetary
formation.
814
01:04:44,000 --> 01:04:55,747
And so, you know, these laser driven laboratory experiments are sort of, you know,
positioned to help us understand uh things about how we, you know, how the component
815
01:04:55,747 --> 01:04:57,928
pieces of the center of Jupiter
816
01:04:57,928 --> 01:04:59,990
How do they behave under those immense pressures?
817
01:04:59,990 --> 01:05:05,714
You have ah millions and millions of atmospheres pressures at the center of Jupiter.
818
01:05:05,714 --> 01:05:08,857
And so how does hydrogen behave?
819
01:05:08,857 --> 01:05:11,199
It turns into a liquid metal.
820
01:05:11,199 --> 01:05:12,940
I mean, that's weird.
821
01:05:13,341 --> 01:05:14,511
We should know more about that.
822
01:05:14,511 --> 01:05:26,271
And so being able to create that state of matter in the laboratory and study how it
behaves has huge implications for our understanding of these gas giants and other even
823
01:05:26,271 --> 01:05:27,772
terrestrial planets.
824
01:05:28,084 --> 01:05:29,495
ah Even our own Earth, right?
825
01:05:29,495 --> 01:05:36,927
There's a lot of really interesting geoscience being done at these laser facilities
through CMAP and otherwise.
826
01:05:37,268 --> 01:05:40,349
And so that's one end.
827
01:05:40,349 --> 01:05:47,492
And then, know, Torit, you can go to these convergence systems like I have that can create
stellar interior relevant conditions.
828
01:05:47,492 --> 01:05:56,346
And so you can start to understand, you know, our own sun, which there are still a lot of
questions about, turns out, even though it's the closest star and we can make a lot of
829
01:05:56,346 --> 01:05:57,412
measurements of it.
830
01:05:57,412 --> 01:06:00,793
You can't really see, you can't send a probe into the center of the sun.
831
01:06:00,953 --> 01:06:03,534
Turns out it'll get incinerated.
832
01:06:03,534 --> 01:06:07,755
And so we don't know even what's, even there's some debate about what's in the sun.
833
01:06:07,755 --> 01:06:13,216
We're not a hundred percent sure what the metallicity, what elements are in the sun.
834
01:06:13,717 --> 01:06:22,529
And that stems largely from disagreement between spectroscopic measurements and uh
helioseismological measurements.
835
01:06:22,529 --> 01:06:25,660
So that's measuring the oscillations of the sun.
836
01:06:25,956 --> 01:06:28,237
and inferring from that the composition.
837
01:06:28,477 --> 01:06:37,460
And so, you know, those are sort of two separate measurements, but they both require
knowledge of, you know, high energy density plasmas and, you know, their equation of
838
01:06:37,460 --> 01:06:37,690
state.
839
01:06:37,690 --> 01:06:40,221
How does sound waves propagate through the sun?
840
01:06:40,221 --> 01:06:46,344
uh That requires knowledge of material properties of hydrogen plasmas at billions and
billions of atmospheres.
841
01:06:46,344 --> 01:06:54,306
uh then, know, spectroscopy requires knowledge of atomic physics and distressing
conditions, know, millions of degrees.
842
01:06:54,507 --> 01:06:55,487
And so,
843
01:06:55,731 --> 01:07:03,718
Being able to create these systems in the laboratories is hugely impactful for
understanding the uh physics.
844
01:07:03,718 --> 01:07:05,579
Or rather, it could be.
845
01:07:05,740 --> 01:07:09,533
I don't think it's living up to its potential uh as of yet, right?
846
01:07:09,533 --> 01:07:20,382
And that large part of that is this, uh there's a large amount of siloing uh in physics in
general, but especially in this field, because you have people who know how to do laser
847
01:07:20,382 --> 01:07:24,621
experiments, and you have people who know how to do astronomy or astrophysics.
848
01:07:24,621 --> 01:07:26,732
And they don't talk usually.
849
01:07:26,732 --> 01:07:28,773
They're in different subfields.
850
01:07:28,773 --> 01:07:34,617
They might meet at a conference, but they don't, you know, they're speaking different
languages effectively.
851
01:07:34,617 --> 01:07:40,240
And so being able to, you know, bring them together and say, Hey, what are the
astrophysical questions we can answer?
852
01:07:40,240 --> 01:07:43,381
You know, cause we're doing these experiments based on what we can do.
853
01:07:43,502 --> 01:07:47,034
And that's not always directly relevant to these astrophysical.
854
01:07:47,034 --> 01:07:53,079
you, you know, bringing in astrophysicists and say, you know, if you could snap your
fingers and we could tell you one thing.
855
01:07:53,079 --> 01:07:56,120
about the matter at the center of Jupiter, what would it be?
856
01:07:56,120 --> 01:07:59,621
And then finding ways to answer that with laser experiments.
857
01:07:59,639 --> 01:08:11,984
And that's one of the missions of CMAP is, I think they're calling it in-reach as opposed
to outreach, talking within the scientific community and trying to break down the walls of
858
01:08:11,984 --> 01:08:23,047
that silo because it's very difficult to merge disciplines when each one is so myopically
focused on what they know and what they know how to do.
859
01:08:23,343 --> 01:08:35,799
uh And then I'll just say the last thing that we're sort of doing is sort of pushing ah
the boundaries uh of these fundamental theories in physics, right?
860
01:08:35,799 --> 01:08:47,654
When you assemble matter to these extreme conditions, you start uh pushing towards the
breakdown of these uh quantum mechanics, special relativity, not general relativity yet.
861
01:08:47,654 --> 01:08:48,834
We can't make black holes.
862
01:08:48,834 --> 01:08:50,095
Everyone always asks me.
863
01:08:50,095 --> 01:08:51,795
So can you make a black hole with this later?
864
01:08:51,795 --> 01:08:54,135
It's like, no, not even close, sorry.
865
01:08:54,295 --> 01:09:01,115
But we can sure get things hot enough where special relativity begins to play a role.
866
01:09:02,255 --> 01:09:13,515
And so what we're able to do by pushing the boundaries of these fundamental theories is to
see where they break down.
867
01:09:13,635 --> 01:09:19,447
Quantum mechanics is sort of always considered in a vacuum, zero temperature, even
isolated atom.
868
01:09:19,447 --> 01:09:23,458
What happens if you put that atom in a dense plasma that's 10 times the density of lead?
869
01:09:23,458 --> 01:09:30,070
It's very difficult to calculate, but we can do it in the laboratory and we can observe
what happens.
870
01:09:30,590 --> 01:09:37,862
So I'll shout out work by my colleague, David Bischel, ah who is measuring, he's a
spectroscopist.
871
01:09:37,862 --> 01:09:47,915
And so he's using implosions and doing spectroscopy on those and seeing how the presence
of this incredibly dense plasma affects the energy levels of your atom.
872
01:09:48,140 --> 01:09:54,876
And it turns out that, you you think of the energy, the quantized energy levels of your
atom is sort of fixed, right?
873
01:09:54,876 --> 01:09:57,187
know, 13.6 EV for hydrogen.
874
01:09:57,208 --> 01:10:00,851
But when you're in a dense plasma, they can actually shift.
875
01:10:00,851 --> 01:10:04,113
can move the energy levels of your atom.
876
01:10:04,113 --> 01:10:08,477
And that's, you know, kind of very complicated to understand and model.
877
01:10:08,477 --> 01:10:16,463
the free electrons are being sort of sucked inside by the nucleus and screening your
energy levels so that the energy levels shift.
878
01:10:16,489 --> 01:10:24,806
And that's sort of changing how we think about quantum mechanics and energy levels and
unbalanced states and free electrons and all that.
879
01:10:24,806 --> 01:10:29,720
And so there's a lot of interesting physics to be done with these giant lasers.
880
01:10:29,720 --> 01:10:37,736
And we're really only just scratching the surface, uh largely because we couldn't really
interpret these measurements too easily until now.
881
01:10:37,797 --> 01:10:45,403
And we live in the information age now with all these diagnostics and Bayesian inference
and machine learning.
882
01:10:46,111 --> 01:10:48,012
Lots of, lots of interesting stuff.
883
01:10:48,493 --> 01:10:49,074
Yeah.
884
01:10:49,074 --> 01:10:49,454
Yeah.
885
01:10:49,454 --> 01:10:51,676
This is, is absolutely incredible.
886
01:10:51,676 --> 01:10:54,718
Um, thanks for, for sharing that on the show.
887
01:10:54,718 --> 01:11:06,828
Definitely add any links that you think are going to be relevant, um, to the show notes
because, I'm sure a lot of listeners are going to want to, uh, to learn more about the
888
01:11:06,828 --> 01:11:13,594
different, topics you just, I mean, research topics you just, you just talked about.
889
01:11:13,594 --> 01:11:15,235
Um.
890
01:11:15,519 --> 01:11:18,850
And so you've been generous with your time.
891
01:11:18,850 --> 01:11:20,621
So I'm going to start playing this out.
892
01:11:20,621 --> 01:11:34,885
I still have a lot of questions for you, but a main one is if, so you see, well, you just
said we're living in a great time now when it comes to diagnostics.
893
01:11:34,885 --> 01:11:41,166
ah Do you see any new diagnostic technologies?
894
01:11:41,166 --> 01:11:43,569
ah Whether that's
895
01:11:43,569 --> 01:11:54,846
novel detectors or quantum sensors or anything else that you're excited about or keeping
an eye on, not only for your work, but for your field in general?
896
01:11:55,087 --> 01:11:55,507
Yeah.
897
01:11:55,507 --> 01:11:59,580
Well, so, I mean, this is a great time for diagnostic development.
898
01:11:59,580 --> 01:12:03,933
We're, you know, at the, at the LLE, we're, we're developing new diagnostics all the time.
899
01:12:03,933 --> 01:12:09,417
You know, many, many PhD thesis are uh devoted to developing these new diagnostics.
900
01:12:09,417 --> 01:12:12,499
um In terms of.
901
01:12:12,713 --> 01:12:20,346
I think the most, you know, the one that I have my eye on uh is there at LEDA developing
the next generation street camera.
902
01:12:20,346 --> 01:12:27,986
uh And so a street camera, basically, it's, you know, just a detector that takes a signal,
an X-ray signal and sweeps it in time.
903
01:12:27,986 --> 01:12:31,261
So you get a continuous record of your X-ray.
904
01:12:31,261 --> 01:12:36,593
So you can use that to take a time resolved spectrum ah or for example, a time resolved
image.
905
01:12:36,593 --> 01:12:42,035
ah And so they're very useful diagnostics, but they always break and
906
01:12:42,411 --> 01:12:46,393
ah You know, there's a joke going around that there's a conservation of street camera.
907
01:12:46,393 --> 01:12:50,775
So, you know, if one is working, that means somewhere in the world, there's another street
camera that is not.
908
01:12:50,895 --> 01:12:55,157
And that holds fairly true for me in my experience.
909
01:12:55,397 --> 01:12:59,119
And so they're working on the next generation that's going to be very robust.
910
01:12:59,119 --> 01:13:04,222
ah it's Sean McPoyle is the graduate student who's developing it.
911
01:13:04,222 --> 01:13:07,103
um And so he's doing a very,
912
01:13:07,409 --> 01:13:16,490
thorough bottom-up approach, know, simulating the electron optics that are required to
build this thing and, you know, building the best possible one, optimizing it from a very,
913
01:13:16,490 --> 01:13:19,082
you know, from first principles approach.
914
01:13:19,082 --> 01:13:28,925
And so that's going to enable really precise ultrafast uh spectroscopy of these, know, uh
billionth of a second lived plasmas.
915
01:13:28,925 --> 01:13:32,606
And that's going to be able to, you know, totally push the boundaries of what we can
measure.
916
01:13:32,606 --> 01:13:34,316
Cause I mean, even, you know,
917
01:13:34,552 --> 01:13:38,243
the officials work looking at these moving energy levels.
918
01:13:38,543 --> 01:13:43,425
That measurement is by modern spectroscopic standpoints terrible.
919
01:13:43,425 --> 01:13:45,725
The resolution is not super great.
920
01:13:45,725 --> 01:13:50,707
The time resolution is not, you can see that the lines move, you don't get much more than
that.
921
01:13:50,707 --> 01:13:58,945
ah And so this next generation is going to be much more, it's going to be higher
resolution, it's going to be better contrast.
922
01:13:58,945 --> 01:14:00,839
And so that's something that I'm really excited about.
923
01:14:00,839 --> 01:14:03,340
It's called the BHX spectrometer.
924
01:14:03,622 --> 01:14:10,507
um The other thing that I'm really excited about, um let's see, we have time resolved
X-ray diffraction.
925
01:14:10,507 --> 01:14:15,851
ah So one thing that we do a lot of, know, X-ray diffraction, standard in material
science.
926
01:14:15,851 --> 01:14:25,908
um We also do it at this sort of nanosecond scale where we blast a sample with a laser and
then we hit it with a bunch of X-rays and you can measure the diffraction peaks that tell
927
01:14:25,908 --> 01:14:27,039
you what structure it's in.
928
01:14:27,039 --> 01:14:32,312
um And so that's told us, you know, we've discovered new uh states of matter.
929
01:14:32,546 --> 01:14:33,847
using that technique.
930
01:14:33,847 --> 01:14:38,309
uh And so it, you know, but it's a single measurement.
931
01:14:38,309 --> 01:14:48,223
And so now we're developing the capabilities to do time resolved diffraction where you're
measuring the movement of those Bragg diffraction peaks with time as you compress it.
932
01:14:48,223 --> 01:14:56,946
So you can see phase transitions happen, which is a really outstanding question in
material science in general is how do phase transitions happen and how do they happen at
933
01:14:56,946 --> 01:14:58,537
extreme conditions?
934
01:14:58,537 --> 01:15:00,758
And so that's going to the very
935
01:15:00,780 --> 01:15:05,554
you know, watching that closely to see what insights that develops.
936
01:15:05,554 --> 01:15:13,911
And then, know, last thing is, you know, the sort of development of high rep rate, you
know, diagnostic technologies.
937
01:15:13,911 --> 01:15:19,305
Cause right now we're in a, you know, we're sitting on sort of a pond of data.
938
01:15:19,305 --> 01:15:22,328
You know, we've been operating the Omega laser since the nineties.
939
01:15:22,328 --> 01:15:27,272
There's a lot of data, but we're taking 10 shots a day, one shot an hour basically.
940
01:15:27,372 --> 01:15:29,732
And that produces a lot of data, but it's, you know,
941
01:15:29,732 --> 01:15:32,812
In terms of, know, compared to particle physics, it's nothing.
942
01:15:32,812 --> 01:15:34,912
Like I could store most of the data.
943
01:15:34,912 --> 01:15:37,771
I can store all the data I've taken from my PhD on my laptop.
944
01:15:37,771 --> 01:15:39,812
And it's not a, not an issue.
945
01:15:40,192 --> 01:15:43,812
Um, but you know, the next generation of lasers coming out are going to be much faster.
946
01:15:43,812 --> 01:15:46,692
They're going to be, you know, dipole or a diode pumped.
947
01:15:47,072 --> 01:15:50,552
And then they're going to be able to fire, you know, on the Hertz scale.
948
01:15:50,552 --> 01:15:54,832
So we're in time, like one shot every five seconds or a minute even.
949
01:15:55,312 --> 01:15:56,411
And so.
950
01:15:56,547 --> 01:16:01,847
that is going to rapidly increase the amount of data that we have just in general.
951
01:16:02,007 --> 01:16:13,127
so understanding what to do with that is a challenge that I think is sort of uniquely
suited for the sort of data science techniques that I've been developing and other
952
01:16:13,127 --> 01:16:15,947
collaborators have been working on to understand that.
953
01:16:15,947 --> 01:16:20,487
And then what can you do if you have a shot every five seconds?
954
01:16:20,487 --> 01:16:24,515
What do you do with that level of repetition rate?
955
01:16:24,515 --> 01:16:29,116
uh What science questions can you answer and then how do you process that data and deal
with it?
956
01:16:29,116 --> 01:16:32,457
How do you even build a target that you can shoot that fast?
957
01:16:32,457 --> 01:16:36,598
And so there's a lot of, I think that's really the frontier of the field.
958
01:16:36,598 --> 01:16:46,701
It's where the field is headed is this high rep rate frontier uh to be able to start
behaving more like other fields where you do a bunch of experiments and you can get very
959
01:16:46,701 --> 01:16:48,522
good statistical certainty.
960
01:16:48,522 --> 01:16:49,782
Yeah.
961
01:16:50,095 --> 01:16:54,283
Actually that reminds me earlier in the show, you were saying that
962
01:16:54,467 --> 01:17:02,021
Um, in one of your projects, the, the data changes with time and space.
963
01:17:02,332 --> 01:17:07,451
so I'm curious how, how are you modeling that if you already are?
964
01:17:09,091 --> 01:17:18,415
um Well, so, I mean, it goes at the end of the day, goes back to, you know, the
hydrodynamic equations, Navier-Stokes, and then, you know, however you want to reduce it
965
01:17:18,415 --> 01:17:18,935
from there.
966
01:17:18,935 --> 01:17:30,220
um And so understanding how it evolves with time and space is, you know, a very
non-trivial physics problem, especially, you know, when you're dealing with laser plasma
967
01:17:30,220 --> 01:17:37,163
coupling and then, you know, beyond just the basic physics questions of what's the
equation of state of this thing.
968
01:17:37,219 --> 01:17:43,199
How does a laser, now you introduce a laser field and transport properties are even less
well understood.
969
01:17:44,099 --> 01:17:51,779
And so, you know, I've sort of adopted of, you know, try and keep things as simple as
possible.
970
01:17:51,779 --> 01:17:54,939
So Newton's, know, keep things at like a Newton's second law level, right?
971
01:17:54,939 --> 01:17:57,219
You balance your forces, right?
972
01:17:57,219 --> 01:18:02,699
The laser is exerting some force on your target and then that necessarily produces an
acceleration.
973
01:18:02,699 --> 01:18:06,403
And so one nice thing about Bayesian inference is you can have these parameters.
974
01:18:06,403 --> 01:18:08,523
that you infer from your data.
975
01:18:08,523 --> 01:18:16,003
So if you have a trajectory of your imploding capsule, you can say, OK, well, I know the
acceleration from these images that I've taken.
976
01:18:16,003 --> 01:18:19,063
I can see this thing converging.
977
01:18:19,063 --> 01:18:21,523
So I know it's going inward.
978
01:18:21,523 --> 01:18:23,783
There must be some force driving that acceleration.
979
01:18:23,783 --> 01:18:26,363
I can refer that from Bayesian inference.
980
01:18:26,363 --> 01:18:34,703
so trying to keep the models as simple as possible without so you don't have to solve the
full Navier-Stokes equation with radiative transfer and all that.
981
01:18:36,675 --> 01:18:45,308
The level that we're at in the future, you know, we'd like to be able to use these
state-of-the-art um Codes these radiation hydrodynamic codes as the model right because
982
01:18:45,308 --> 01:18:56,355
that's a complete picture of all the physics involved The problem is there's you know,
they're slow, you know, they're taking hours to run one simulation and they're also you
983
01:18:56,355 --> 01:19:05,333
know, there's a lot of parameters in these very complicated codes as you can imagine and
So, you know the sort of future is to build a sort of Bayesian version
984
01:19:05,499 --> 01:19:13,467
of one of these codes that's ideally written in Python, ah fully differentiable with
respect to the parameters and much faster.
985
01:19:13,467 --> 01:19:19,433
And probably that looks something like building a neural network surrogate ah of one of
these codes or something.
986
01:19:19,433 --> 01:19:27,581
um We'll see what the future holds, but that's the dream is to move to more and more
complex physical models.
987
01:19:27,581 --> 01:19:28,700
uh
988
01:19:28,700 --> 01:19:32,301
sort of trying to follow the blueprint that the particle physics people do.
989
01:19:32,301 --> 01:19:36,322
They have this very complicated, complete physical model and they use that to make
predictions.
990
01:19:36,322 --> 01:19:42,214
And so we'd like to be able to do the same and then infer using the best available models.
991
01:19:43,034 --> 01:19:46,095
for now, very simple, very simple pictures.
992
01:19:46,135 --> 01:19:46,770
Yeah.
993
01:19:46,770 --> 01:19:52,016
I mean, you have to start somewhere, especially with all the complexities you were talking
about before.
994
01:19:52,537 --> 01:19:56,538
And the block building philosophy, you were...
995
01:19:56,538 --> 01:19:57,832
uh
996
01:19:57,832 --> 01:20:03,407
talking about, which I definitely agree with, because that way, know, what is working and
what is not.
997
01:20:03,407 --> 01:20:04,618
So that's extremely helpful.
998
01:20:04,618 --> 01:20:10,173
Now I was asking because me, I hear spatial temporal and I think about Gaussian processes,
of course.
999
01:20:10,173 --> 01:20:11,294
you know, like I was curious.
1000
01:20:11,294 --> 01:20:12,334
of course.
1001
01:20:12,675 --> 01:20:16,628
And that's part of the simple model, right?
1002
01:20:16,628 --> 01:20:18,730
When you don't know how something evolves in time, right?
1003
01:20:18,730 --> 01:20:19,981
The temperature is a great example.
1004
01:20:19,981 --> 01:20:25,756
That's, you know, depends on all of the thermal processes, conduction, radiative heating,
you know, expansion.
1005
01:20:25,756 --> 01:20:28,567
All of those things go into that and it's very difficult to model that.
1006
01:20:28,567 --> 01:20:32,808
ah But you know, the temperature goes up and then down.
1007
01:20:32,808 --> 01:20:37,379
And so the perfect sort of vehicle for that is of course, modeling as a Gaussian process.
1008
01:20:37,379 --> 01:20:42,601
And that's an infinitely flexible tool for that and something we've we've leaned on a lot.
1009
01:20:42,601 --> 01:20:43,031
Yes.
1010
01:20:43,031 --> 01:20:45,771
I forgot you're big fan of Gaussian processes.
1011
01:20:45,771 --> 01:20:47,652
I should have led with that.
1012
01:20:48,112 --> 01:20:48,512
I am.
1013
01:20:48,512 --> 01:20:48,932
am.
1014
01:20:48,932 --> 01:20:55,684
So did you try actually some GPs on that or that actually doesn't work because
1015
01:20:55,684 --> 01:21:05,921
When the data is too big or even better justification would be, well, we know more
structure than we can impose on a GP.
1016
01:21:06,341 --> 01:21:06,902
No, yeah.
1017
01:21:06,902 --> 01:21:09,703
Well, so we use Gaussian processes.
1018
01:21:09,914 --> 01:21:15,087
I mean, I use Gaussian processes at every available opportunity just because they're a
very powerful tool.
1019
01:21:15,087 --> 01:21:19,871
So what we'll often do is model a piece of the model.
1020
01:21:19,871 --> 01:21:23,873
For example, the temperature history is a function of time as a Gaussian process, right?
1021
01:21:23,873 --> 01:21:24,988
m
1022
01:21:24,988 --> 01:21:28,430
That's sort of, know, there's stuff that we know more about, right?
1023
01:21:28,430 --> 01:21:35,583
That the Newton's second law piece, I was talking earlier, there's physics pieces that we
know and when possible we use the physics.
1024
01:21:35,943 --> 01:21:41,225
But you know, when you can't, you want to use something that is flexible and able to
capture the data.
1025
01:21:41,225 --> 01:21:45,467
ah Well, you know, we know the temperature is a continuous function of time.
1026
01:21:45,467 --> 01:21:49,469
And so Gaussian process is the perfect sort of prior to place on that.
1027
01:21:49,949 --> 01:21:51,760
And sort of, you know.
1028
01:21:51,760 --> 01:21:56,994
lets the data inform what that is while giving an estimate of the uncertainty.
1029
01:21:59,417 --> 01:22:00,898
Yeah.
1030
01:22:00,898 --> 01:22:01,668
Great.
1031
01:22:01,668 --> 01:22:04,040
This is a very interesting thing to do.
1032
01:22:04,230 --> 01:22:15,670
And both in Amparo and Pinesy, have very good GP modules that you can use flexibly um in
your models without forcing the model to be a pure GP.
1033
01:22:15,670 --> 01:22:19,293
So this is something extremely, extremely helpful.
1034
01:22:19,293 --> 01:22:20,854
um
1035
01:22:21,794 --> 01:22:27,198
Maybe a few more questions before I ask you the last two questions.
1036
01:22:27,198 --> 01:22:34,042
I promise I won't be too long, but I'm curious now, playing this out, thinking a bit more
about the future.
1037
01:22:34,042 --> 01:22:37,624
What's your vision for scaling up experiments?
1038
01:22:37,925 --> 01:22:42,127
Whether that's energy, repetition rate, fidelity.
1039
01:22:42,308 --> 01:22:51,233
In the next few years, what do you hope the field will get when it comes to scaling up
experiments?
1040
01:22:51,521 --> 01:22:54,344
Yeah, well, so it's going to be a sort of two pronged approach.
1041
01:22:54,344 --> 01:23:01,609
think what we're already seeing is a move towards high rep rate at existing facilities.
1042
01:23:01,810 --> 01:23:08,295
So the sort of most prominent example is the dipole laser at the European Exfel in
Hamburg, Germany.
1043
01:23:08,295 --> 01:23:16,102
And so they've built a reparated sort of Joule class laser that can do, you know, one
shot.
1044
01:23:16,102 --> 01:23:19,945
It's supposed to be, I think one Hertz, but it's not quite there.
1045
01:23:19,993 --> 01:23:27,618
ah It can shoot every couple minutes or so, which is much better than the previous
version, which had like an hour cool time or whatever.
1046
01:23:27,618 --> 01:23:36,083
And so now you can just rattle through a bunch of different targets and you can do
someone's whole PhD thesis in an hour.
1047
01:23:36,083 --> 01:23:45,058
ah And so I think moving that direction, this high rep rate is very, um that's where we're
heading.
1048
01:23:45,058 --> 01:23:46,861
And I think that's a good direction to head.
1049
01:23:46,861 --> 01:23:51,082
The other piece is going to be, we're going to need to build new facilities.
1050
01:23:51,082 --> 01:23:56,024
And, you know, the Omega laser is, as I mentioned several times, very old.
1051
01:23:56,024 --> 01:23:57,104
It's from the nineties.
1052
01:23:57,104 --> 01:23:59,305
It's using nineties laser technology.
1053
01:23:59,305 --> 01:24:00,345
It's showing its age.
1054
01:24:00,345 --> 01:24:02,906
um And it's a really good facility.
1055
01:24:02,906 --> 01:24:03,846
It does really good work.
1056
01:24:03,846 --> 01:24:11,828
um But we're going to have to start thinking about the next generation of laser drivers to
be able to sort of keep pushing the boundaries.
1057
01:24:11,828 --> 01:24:14,209
And so obviously the national ignition facility.
1058
01:24:14,209 --> 01:24:17,151
out at Livermore is uh mega joules.
1059
01:24:17,151 --> 01:24:21,973
So it's 10 times bigger than the Omega 60 laser, which is only 30 kilojoules.
1060
01:24:22,273 --> 01:24:30,869
And so that serves its own purpose, but you can only shoot that once a day because it's so
massive, the lamps take forever to cool down.
1061
01:24:30,869 --> 01:24:38,292
And then you create so many neutrons from your fusion reactions that it uh makes the whole
chamber radioactive.
1062
01:24:38,292 --> 01:24:43,929
so there, think, is a middle ground here sort of between the
1063
01:24:43,929 --> 01:24:53,883
kilojoule class laser that Omega is now and the mega joule laser at NIF, you know,
probably like a hundred kilojoules is probably the sweet spot uh where it's also, you you
1064
01:24:53,883 --> 01:25:02,907
were, you're able to rep rate that and do all of, all of the, the cool science that the
Omega 60 laser does now uh and more, right?
1065
01:25:02,907 --> 01:25:11,141
Cause you have a little bit more energy, but it being able to do that at scale at rep
rate, I think is going to do, would be a very worthwhile endeavor.
1066
01:25:11,141 --> 01:25:21,420
And we'll see there, you know, they're in discussions to build the next generation of
Omega 60 which is sort of tentatively named the unimaginative Omega next Which I think is
1067
01:25:21,420 --> 01:25:33,160
a terrible name and needs to be changed before we start proposing it to the government but
um Yeah, I think that's that's the way the way forward is reparate and you know more
1068
01:25:33,160 --> 01:25:38,825
energy But you know, I don't think we need to go, you know, people are talking about
building nif to
1069
01:25:39,126 --> 01:25:44,270
uh Right, because now that they got ignition over there, we need to build a 10-megajoule
laser.
1070
01:25:44,270 --> 01:25:50,213
And that's great, but I think there's a lot more interesting scientific questions that can
be answered with a 100-kilojoule laser.
1071
01:25:50,213 --> 01:25:54,877
uh Like Omega 60, but Omega next.
1072
01:25:54,877 --> 01:25:55,897
Damn, yeah.
1073
01:25:55,897 --> 01:26:00,981
Yeah, that sounds like a powerful beast to build.
1074
01:26:00,981 --> 01:26:06,384
um Now, one last question before the last two questions.
1075
01:26:06,384 --> 01:26:07,845
um I know...
1076
01:26:08,327 --> 01:26:16,368
So you're, you're maybe starting to teach it or at least you're, you're doing some
Bayesian outreach as you were saying.
1077
01:26:16,368 --> 01:26:24,121
So I'm curious what advice do you younger scientists entering the field?
1078
01:26:24,441 --> 01:26:29,363
What skills, mindset, training do you think are most critical?
1079
01:26:30,063 --> 01:26:30,413
Yeah.
1080
01:26:30,413 --> 01:26:37,778
Well, I think it's one thing I wish, you know, people had told me, and I think a
misconception about
1081
01:26:37,778 --> 01:26:43,872
you know, grad school in general, is I tell people I'm doing, you know, I PhD in physics
and I'm like, you must be so smart.
1082
01:26:43,872 --> 01:26:45,453
You must be a genius.
1083
01:26:45,573 --> 01:26:48,155
And it's like, I don't think that's necessarily true.
1084
01:26:48,155 --> 01:26:52,398
I think more than anything, it's mental toughness is what you need to cause it.
1085
01:26:52,398 --> 01:26:54,319
Grad school is a grind.
1086
01:26:54,479 --> 01:26:57,321
And there are, there are days when you're like, I hate this.
1087
01:26:57,321 --> 01:26:58,001
I want to quit.
1088
01:26:58,001 --> 01:27:02,945
Um, and you know, there are, you know, just as many days where like, you know, this is
great.
1089
01:27:02,945 --> 01:27:06,597
Like I, I feel like I'm unraveling truths of the universe.
1090
01:27:06,799 --> 01:27:13,271
And being able to sort of manage those highs and lows takes a remarkable amount of mental
toughness.
1091
01:27:13,271 --> 01:27:21,883
And so what I've seen over the course of my career is graduate students who are successful
are ones who are able to grind it out.
1092
01:27:22,123 --> 01:27:24,444
And it helps to have a sense of community.
1093
01:27:24,444 --> 01:27:30,585
And so that would be my other piece of advice is make friends with your lab mates and
fellow grad students.
1094
01:27:30,926 --> 01:27:34,746
it'll get better, allegedly.
1095
01:27:36,903 --> 01:27:44,430
it's, it's important to, to have mental toughness and not lose sort of the big picture,
uh, side of it all.
1096
01:27:44,430 --> 01:27:44,620
Right.
1097
01:27:44,620 --> 01:27:51,697
Cause it, you know, well, you're doing cutting edge science in, it's, it's very, uh, you
know, remarkable in that sense.
1098
01:27:51,697 --> 01:27:57,512
And so being able to not lose sight of that while maintaining your, your toughness is, is
I think that's the key to success.
1099
01:27:57,512 --> 01:27:59,163
That's, that's my advice.
1100
01:28:01,073 --> 01:28:01,373
Yeah.
1101
01:28:01,373 --> 01:28:02,243
Yeah.
1102
01:28:02,243 --> 01:28:16,834
So resilience and compounding effect of small daily grind is, definitely something you
recommend and definitely push to with my own students.
1103
01:28:16,834 --> 01:28:20,617
Like, because I get the same, yeah, I guess the same reactions.
1104
01:28:20,617 --> 01:28:27,372
Um, each time I talk to people about what I do and it's always like, oh yeah, I'm not good
at math.
1105
01:28:27,372 --> 01:28:29,183
know, I've never, it's not for me.
1106
01:28:29,183 --> 01:28:29,939
Um.
1107
01:28:29,939 --> 01:28:38,379
And I think trying to develop more of that growth mindset where it's well, you know, I'm
not sure it's for me either.
1108
01:28:38,379 --> 01:28:41,579
You know, it's just, I, I love it and I love learning new things.
1109
01:28:41,579 --> 01:28:48,379
And I think working on difficult problems is the best way to learn new things because
otherwise I get bored.
1110
01:28:48,379 --> 01:28:56,811
But this is extremely uncomfortable and hard because by definition, if you're always at
the frontier of the field you work in.
1111
01:28:57,115 --> 01:28:59,016
You're working on things that aren't solved yet.
1112
01:28:59,016 --> 01:29:10,224
And so you don't have that feeling of, uh, yeah, being comfortable because you never know
exactly how you're going to solve what you're working on.
1113
01:29:10,224 --> 01:29:12,665
And so, even if there is a solution.
1114
01:29:12,946 --> 01:29:13,516
Yeah.
1115
01:29:13,516 --> 01:29:14,657
Well, so that's even worse.
1116
01:29:14,657 --> 01:29:15,327
Yeah.
1117
01:29:15,327 --> 01:29:18,290
That's not up in that Pandora's box, but yeah, yeah, no, for sure.
1118
01:29:18,290 --> 01:29:21,055
Um, yeah, you don't even know if there is a solution.
1119
01:29:21,055 --> 01:29:26,715
Um, and, and so, yeah, I think having.
1120
01:29:27,347 --> 01:29:33,727
loving what you're working on because it gives you something you really value.
1121
01:29:34,607 --> 01:29:47,287
And just being able to persistently get point one percent better every day is going to
give you a very valuable compounding effect.
1122
01:29:47,907 --> 01:29:49,207
100 % agree.
1123
01:29:50,767 --> 01:29:51,187
Awesome.
1124
01:29:51,187 --> 01:29:57,013
Well, Ethan, I think it's time to let you go because as you've seen in the Google doc app.
1125
01:29:57,013 --> 01:30:00,546
I have more questions, but let's call it a show.
1126
01:30:00,546 --> 01:30:06,090
um But before letting you go, of course, you know, I'm going to ask you the last two
questions.
1127
01:30:06,090 --> 01:30:07,932
I ask every guest at the end of the show.
1128
01:30:07,932 --> 01:30:14,997
ah So first one, if you had unlimited time and resources, which problem would you try to
solve?
1129
01:30:15,518 --> 01:30:18,100
So, all right, this is a bit of a niche one.
1130
01:30:18,921 --> 01:30:25,886
But I'm very interested in this idea of picnonuclear fusion.
1131
01:30:26,438 --> 01:30:28,610
And so, you know, most people are familiar with thermonuclear fusion.
1132
01:30:28,610 --> 01:30:29,921
That's what happens in the sun, right?
1133
01:30:29,921 --> 01:30:33,443
have, you know, hydrogen molecules, very hot, they crash into each other and they fuse.
1134
01:30:33,443 --> 01:30:45,111
ah There's another mechanism that's believed to occur in some super dense astrophysical
objects, like in white dwarfs, for example, where you have sufficient density that you
1135
01:30:45,111 --> 01:30:52,456
have, you know, two atoms that are close enough together that they spontaneously fuse, not
due to, you know, high velocity collisions, but just because of proximity.
1136
01:30:52,776 --> 01:30:55,818
And if it, you know, it sounds a lot like a cold fusion.
1137
01:30:55,948 --> 01:30:59,941
But this is a little bit more uh scientifically sound.
1138
01:30:59,941 --> 01:31:09,929
And so there's a longstanding uh belief of my advisor that you can do this on a laser
facility like the National Ignition Facility.
1139
01:31:10,290 --> 01:31:13,812
But you would need to make it incredibly high density.
1140
01:31:14,453 --> 01:31:18,497
incredibly, you'd have to keep it cold enough that thermonuclear fusion doesn't happen.
1141
01:31:18,497 --> 01:31:25,272
And so if the government gave me unlimited time and money, I would just devote the entire
time of the National Ignition Facility.
1142
01:31:25,272 --> 01:31:28,343
to trying to make as dense of an object as I could.
1143
01:31:28,343 --> 01:31:31,334
And maybe we'd get the black hole that everyone always asks me about.
1144
01:31:31,334 --> 01:31:38,786
But ideally, you'd show this peak no nuclear fusion is, I think, one of the coolest
things.
1145
01:31:38,786 --> 01:31:45,368
um And it's a largely unsolved problem because we have no idea what's happening in those
white wars.
1146
01:31:45,368 --> 01:31:49,209
And we can't yet make that plasma in the laboratory.
1147
01:31:49,209 --> 01:31:50,629
So that's the problem.
1148
01:31:50,629 --> 01:31:54,090
It's personal pet project.
1149
01:31:55,926 --> 01:31:56,346
Okay.
1150
01:31:56,346 --> 01:31:58,127
Yeah.
1151
01:31:58,127 --> 01:31:58,887
I love that.
1152
01:31:58,887 --> 01:32:05,789
um niche answers are definitely encouraged to that question.
1153
01:32:05,789 --> 01:32:08,230
em Second question.
1154
01:32:08,230 --> 01:32:15,371
If you could have dinner with any great scientific mind, dead alive, alive or fictional,
who would it be?
1155
01:32:15,432 --> 01:32:24,394
So this is going to be controversial given the, he was kind of a villain in Oppenheimer,
but I'm going to go with Ed Teller.
1156
01:32:24,702 --> 01:32:36,562
Uh, just because, you know, he's, he's sort of a controversial figure, uh, in, scientific
history, but I think he, I think he had a very interesting view on science and sort of,
1157
01:32:36,562 --> 01:32:37,837
uh, interesting mind.
1158
01:32:37,837 --> 01:32:39,728
And I would love to sort of pick his brain.
1159
01:32:39,728 --> 01:32:50,593
He also, um, you know, a lot of the work that he did, uh, you know, post Manhattan project
set laid the groundwork for, you know, the high energy density physics as we know it
1160
01:32:50,593 --> 01:32:51,353
today, right?
1161
01:32:51,353 --> 01:32:54,190
He was using nuclear bombs and set of giant lasers.
1162
01:32:54,190 --> 01:32:55,451
uh as a driver.
1163
01:32:55,451 --> 01:33:00,423
um But it would be interesting to sort of pick his brain about the foundations of the
field.
1164
01:33:00,423 --> 01:33:07,898
And of course, he helped invent the uh Metropolis-Hastings uh algorithm that is the
foundation of all Bayesian inference.
1165
01:33:07,898 --> 01:33:10,119
I'd be interested to talk to him about that.
1166
01:33:10,119 --> 01:33:10,619
Damn.
1167
01:33:10,619 --> 01:33:11,220
Yeah.
1168
01:33:11,220 --> 01:33:12,700
Yeah, great answer.
1169
01:33:12,700 --> 01:33:17,043
And I think you're the first one to actually answer that.
1170
01:33:17,043 --> 01:33:18,564
I would not be surprised.
1171
01:33:18,564 --> 01:33:20,304
I don't think that's a very popular answer.
1172
01:33:20,304 --> 01:33:23,453
um
1173
01:33:23,453 --> 01:33:27,214
Awesome, well, Ethan, thanks again for being on the show.
1174
01:33:27,214 --> 01:33:28,595
That was fantastic.
1175
01:33:28,595 --> 01:33:31,666
You were able to cover so much ground.
1176
01:33:31,906 --> 01:33:34,687
I am very happy about that.
1177
01:33:34,807 --> 01:33:36,478
You're doing fascinating work.
1178
01:33:36,478 --> 01:33:40,489
So I am extremely happy to have you on the show.
1179
01:33:40,489 --> 01:33:45,151
Let's make sure to add all these great resources to the show notes.
1180
01:33:45,151 --> 01:33:47,332
I've already added a few of them, folks.
1181
01:33:47,332 --> 01:33:52,654
So make sure to check them out if you want to dig deeper.
1182
01:33:53,104 --> 01:33:57,622
Ethan, thanks again for taking the time and being on this show.
1183
01:33:57,622 --> 01:33:58,809
Thank you so much for having me.
1184
01:33:58,809 --> 01:34:02,690
And thanks again to JJ Ruby for putting this in.
1185
01:34:07,028 --> 01:34:10,721
This has been another episode of Learning Bajan Statistics.
1186
01:34:10,721 --> 01:34:21,230
Be sure to rate, review and follow the show on your favorite podcatcher and visit
learnbastats.com for more resources about today's topics as well as access to more
1187
01:34:21,230 --> 01:34:25,313
episodes to help you reach true Bajan state of mind.
1188
01:34:25,313 --> 01:34:27,255
That's learnbastats.com.
1189
01:34:27,255 --> 01:34:32,119
Our theme music is Good Bajan by Baba Brinkman, fit MC Lars and Meghiraan.
1190
01:34:32,119 --> 01:34:35,261
Check out his awesome work at bababrinkman.com.
1191
01:34:35,261 --> 01:34:36,456
I'm your host.
1192
01:34:36,456 --> 01:34:37,517
Alex and Dora.
1193
01:34:37,517 --> 01:34:41,666
can follow me on Twitter at Alex underscore and Dora like the country.
1194
01:34:41,666 --> 01:34:48,935
You can support the show and unlock exclusive benefits by visiting Patreon.com slash
LearnBasedDance.
1195
01:34:48,935 --> 01:34:51,316
Thank you so much for listening and for your support.
1196
01:34:51,316 --> 01:34:53,618
You're truly a good Bayesian.
1197
01:34:53,618 --> 01:35:00,422
Change your predictions after taking information and if you're thinking I'll be less than
amazing.
1198
01:35:00,422 --> 01:35:03,725
Let's adjust those expectations.
1199
01:35:03,725 --> 01:35:06,234
Let me show you how to be a good Bayesian.
1200
01:35:06,234 --> 01:35:16,937
You change calculations after taking fresh data in Those predictions that your brain is
making Let's get them on a solid foundation