Episode Transcript
Ridiculous History is a production of iHeartRadio.
Welcome back to the show.
Thank you, as always so much Ridiculous Historians for joining us.
Let's hear it for the man the myth our super producer mister Max Williams Imax.
All right, yeah, we're getting some snapping fingers.
This is part two of a continuing exploration.
The guy who just said Imax is mister Noel Brown, none other than.
Speaker 2Oh thanks buddy, You're welcome, Buckeroo.
Speaker 1They called me Ben Bullen in this part of the world, and Noel, if we could do a previous on Ridiculous History, the smoke Monster was bullsh wasn't anything, well, it was the thing.
It was the man in Black, it was you know, that's the show Lost, which dated references.
Speaker 2But that's what we're here for.
No, it's true.
Speaker 3We did previously on Ridiculous History talk with the brilliant and lovely doctor Jorge at Sham, who helped us navigate the universe a little bit, from the Big Bang to the singularities to AI and the way that artificial intelligence may well be close to, if not already at a place where it resembles the human brain.
Speaker 1Yes, that is true.
And Noel, as you know, I'm really proud of you and Maxim myself for being quite transparent and forthright with the fact that we are ourselves not experts.
Speaker 2Folks.
Speaker 1We know everybody enjoyed the first part of our conversations with doctor or a Champ, and believe it or not, we were able to get Orgey back for another episode or Hey, welcome, thank you for joining us.
Speaker 4Hey, super fun to be here.
Thanks for having me back.
Speaker 3Of course, of course you're helping us out as well.
We love a good two part, especially one that we decide on in advance.
Speaker 4Yeah, and this will be the Empire Streks back of podcasts.
Speaker 2Oh, that's the film.
It's a universe.
Speaker 1We're talking about the history of what we call the Big Bang in our previous exploration, which led us to, as you were saying, Noel, an exploration of so called artificial intelligence, the nature of reality, the observable universe.
And we tease just a bit episode two.
This is our exploration of the ridiculous history of a thing that studies itself the science of the human brain.
So real quick I could if we could open it up this way, Orgey, just small talk, What is the human brain.
Speaker 4Was this little about sixty eight pound organ that you have in your head.
And it's just another organ in your head.
Speaker 1You know.
Speaker 4It's a lump of fleshy stuff that basically makes who you are happen, Like your conscious experience, all your memories, how you feel, that's all happening in that little gelatinous blob inside your skull.
Speaker 3I've always felt calling the brain an organ was selling it short just a little bit.
When I think of an organ, I guess I think of just like guts.
You know, it's important.
But the brain is a very peculiar and powerful and incredible organ.
Speaker 4It is it is.
People say it's the most complex organization of matter that we know about in the whole universe.
Speaker 2And it's also the biggest erogenoist one.
Speaker 4In the human we go.
It's the biggest everything one.
Basically hunger, heye, love, it's all happening in your head.
Speaker 1Now, this is fascinating.
I love that phrase because we also have to acknowledge an inherent dilemma.
We're asking a thing to research and explain itself, to measure itself.
Could you tell us a little bit about the philosophical quandaries involved with that like because ordinarily, you know, if you asked if you asked a duck its opinion about ducks, you would get a weird you know, not completely objective.
Speaker 4Right, right, right, and everyone knows are just a bunch of quacks.
Now it's a super interesting philosophical conversation, right, because right, there's eighty six billion neurons in your head, and so the idea that eighty six billion neurons could ever really really understand what's happening in eighty six billion neurons, even if somebody else's eighty six billionaires, it's sort of impossible, right.
It's sort of like a car understanding a car, or you know, a switch understanding a switch.
So it's probably not possible for the human brain to really understand everything that's going on in your brain, like down to the tee.
But you know, we have science, and so we can make kind of generalizations, we can make certain rules, we can understand the general structure and organization of the brain, but like totally understanding the brain and predicting what it's going to do, it's probably impossible for our brains.
But you can imagine, like maybe aliens who have four hundred billion neurons, you know them, we might be like, oh, look at these cats, you know, running around, We can totally understand what's going on in their heads.
Speaker 1So this leads us to the ridiculous history of neuroscience or brain science.
Could you tell us a little bit about the first I guess there was a moment in human civilization, or a series of moments more accurately, wherein people realized this gelatinous blob in their head was doing something.
We're under the impression that for a lot of human history, various cultures believed that the soul or the consciousness maybe resided in other organs, like the heart or the I'll say it, sorry, substitute teachers, genitalia.
Speaker 4Was there a lot of it?
A lot of our actions do come.
Speaker 2From it's like a second brain.
Speaker 1So what was there any sort of inflection point or crossroads in history of humans where they started to look at the brain as a seat of consciousness.
Speaker 4Yeah, yeah, now, yeah, it's a pretty interesting history because, as you mentioned, probably for most of human history, we had no idea what was going on inside of our bodies.
How though our bodies work, much less how our brains worked or what it did Aristotle back in the ancient Greek era.
Uh, basically agree with what you just said, which is he thought that everything that makes us who we are is in our hearts, like in our chest.
And he thought that the brain was really just like a radiator, like a brain just there to like cool people.
Yeah, jes United has all these like lumps and wriggles like that would make sense, right kind of.
Speaker 2Yeah, sure, maybe dissipute the heat like coils like coils in.
Speaker 4Area, Yeah, yeah, like increasing the surface area.
Speaker 2Uh.
Speaker 4And if you think about it, it kind of makes sense, right, Like if you are designing a human being, Like, why would you put the most important part on this little like appendage sitting at the top, you know, exposed to Yeah it's exposed.
Yeah yeah what did you put it?
Like in the chest right protected by ribs and organs Like that would make a little bit more sense.
But no, it's like it's sticking up in our hands.
It's a little peninsula on the box.
Yeah yeah, so easy to knock or or chop off.
So he didn't quite have it right, But people think that maybe the Egyptians knew a little bit more about the brain.
So there's this famous papyrus papyrus scroll, yeah, that they found made by the ancient Egyptians where they kind of like documented medical cases.
It's called the Edwin Smith Papyrus.
Speaker 2Yes, like the thought yeah.
Speaker 4Oh that's another brain game right there.
So we know, like the Addigus catalog all these medical things like oh, if you break an arm, this is what happens.
If you sever your spinacle, this is what happened.
And there's like an entry number twenty in this squirrel that says, you know, if you get hit in the head card, we know that sometimes you can lose the ability to talk.
So like in their heads they're thinking, oh, your brain is good for things like talking.
So that's kind of like the earliest we think kind of a record of people humans kind of understanding what the brain is doing.
Speaker 2Oh wow.
Speaker 1And this this also reminds us clearly of a similar practice indicative of recognizing the importance of the brain as an organ, which is the practice of trepan nation, right.
Uh, trepanation being.
Speaker 2The demons.
Speaker 1Yeah yeah, yeah, yeah, venting relieving pleasure, yeah, drilling a physical hole somewhere in the cranium.
I think for a lot of us lay for the primary amazing thing about the practice of trapanation is that people survived somehow.
Speaker 4Yeah right, Yeah, it's wild.
Basically, there's not much activity going on like understanding the brain up until about the eighteen hundreds, and that's when people really started to record things like hey, if you open up your skull and you dig a hole through here, this can happen.
Or if you open up this part of the brain and you kind of like mess around with it or apply electricity like that, your arm will move and so yeah, so that's one of the things that people did in the eighteen hundreds, which which opened up your brain and pok it.
And it's sort of dubious to us.
Speaker 2Now that's not to say.
Speaker 3Syram that gave us that information, but which is often the case with early discovery, it's like, yeah, you know, you gotta break a few eggs to make a science online.
Speaker 4Be a little bit of a mad scientist.
Yeah, but it taught us a lot, Like it started to kind of piece everything together.
People started to figure out, oh, like the brain has parts.
You know, it's not just like one giant computer chip.
It's got like a little processor for this over here and a little processor for that out over there, and so that's kind of how it started, really kind of ramping up the history of brain science.
Speaker 1Now we're talking the eighteen hundreds at this point, which means from what Noel and I understand, this means this happens, this great scientific inquiry occurs in the same sort of historical milieu as a lot of quack science.
Right, I guess we should talk about phrenology a little bit.
Speaker 4Yeah, yeah, yeah, Well it's it's sort of a it's a bit of a sketchy thing to delineate between quack science and really thought right, you know what I mean.
Like back then, it's like it's like accusing a cavement of not being good scientists.
You know, they just didn't know, and so they were just trying all these different theories.
They had all these ideas.
They were going on vibes basically vibes, and yeah, it's a Phrenology was a huge deal in the eighteen hundreds.
People thought that, you know, there was this idea that the brain is mapped, like there's areas that do different things.
But so people would just guess, like, oh, the part of the back part of your rank, that's where that's where your love is located and the front part is where your egoism is located, and so they just if you look it up phrenology, there's all these like maps.
I think most people have probably have probably seen them, just like a human head with like areas kind of like a like a meat diagram and a cow for one little.
Speaker 2Regions where the tenderline is exactly.
Speaker 4Yeah, yeah, yeah.
Speaker 1And that was informed, unfortunately by a lot of confirmation bias, we could argue from Western Europe at the time, wherein people would say, oh, we've made this rough Butcher's diagram or topography of a cranium, and based on this bump, this guy is going to be good at what's a silly thing to be good at?
Speaker 2In the unicycle.
Speaker 1This guy's great at unicycles.
Yeah, look at the other bump, you know, right there by the temple.
This is our unicyclist juggler phrenology.
Speaker 2Jorge.
Speaker 1Was it widely accepted in its day.
Speaker 4I think it was, you know, as accepted as like you know, somebody selling tonics, you know, going from town to town in the Old West selling tonics to rejuvenate your vigor or something like that.
You know, it's something that people weren't quite sure it was true or not, and some people claim that they were starting up it and you know, people rolled the dice.
Speaker 3Not a far jump from things like the humors, you know, the idea of leeching and blood letting in order to balance out these supposed you know, materials within the body.
And then honestly, I'm not trying to poop anybody's beliefs here, but not too too far off from things like chakras and meridian lines in some you know, Eastern medicine that some people think is quackery and some people swear by.
So I mean, it's just interesting the way some of that stuff is still around and believed in or not believed in depending.
Speaker 4No, no, that stuff is quackery.
Speaker 2No okay, Oh the.
Speaker 1Professor came out on that one.
Speaker 4No fense to the Crystal fans.
Speaker 2Yes, yes, yes, we just being diplomatic.
Speaker 1We are being diplomatic, and we we share the same pursuits, which is always going to be hopefully the collective, objective interrogation of the world around us and within us.
One thing we were talking about a little bit off air.
It pertained to some some just phenomenal and again, as you said Jorge.
Ethically, dubious learnings that came.
You mentioned the earlier realization from humanity that certain parts of the brain function in certain ways right and excel in certain things.
And at the end of our first conversation we introduced a patient who for a long time was simply known as HM, and HM, as we find, is pivotal to neuroscience, perhaps because of well, gosh, can we tell can we tell the story?
Yes, super fasting story.
This was a little bit later.
This was in the nineteen thirties that this man came about.
His name was Henry Malaysan, but for a long time people didn't know his name because when you become a medical subject, they kind of make you anonymous.
So for a long time, for many years, he was just known as patient AHM.
And so this was a guy who had a lot of seizures as a kid.
Some people think it maybe happened after he had like a bike accident and then he knocked his head.
Some people think he was just kind of he just had these seizures for no reason.
So it's not quite clear how or why he got these features, but they were like super intense, like he couldn't really function it would really kind of make him not able to have a job or go to school or things like that.
Speaker 4And at the time, as you said, the doctors were like, oh, I know how to cure it this.
I'll just poke a hole in your head and mess around with it.
And so a common procedure back then was basically a lobotomy, Like they would just kind of stick this long needle kind of through your eye socket, did you like move your eye a little bit out of the way, and then you stick it in there and then kind of mess around.
And what they did for him specifically was they destroyed most of his hippocampus, so like deep inside your brain you have this little these little lumps called the hippocampus.
And you know, his seizures were so severe that this doctor called Williams Coville thought that he needed to take out both his hippocampus, and so he did.
And the amazing thing is it sort of worked, like his seizure stopped.
But unfortunately it had a bad side effect, which is that Henry Molaysan was not able to make new memories.
So like he remembered his whole life, his childhood, you know, his early adulthood, right up until the day he had his surgery.
But after that he couldn't remember more than thirty minutes at a time.
Speaker 1He couldn't encode information.
Speaker 4Right, Like if you met him and you said hey, and he like, he could tell you where he grew up, who his mother was, and everything, but thirty minutes later he would totally forget he met you, Or thirty minutes later, he couldn't tell you how he got to where he was, what he had for breakfast, you know, any he couldn't tell you anything beyond thirty minutes ago.
Speaker 1Okay, well, we've all met executive producers and before you see.
Speaker 4A botimized Oh.
Speaker 1So this this is a moment of tremendous significance to the history of neuroscience when and first off, him's existence at this point is cursed.
You mentioned earlier that this was this was a primary source for the film Momento.
Speaker 2Is that correct?
Speaker 4Yeah, the Christopher Nolan film The When He Got kind Of I got famous for initially Memento.
It was this guy who basically lived this life, but in our modern world right now and so he couldn't remember more than thirty minutes ago, and so and so that movie's kind of told backwards in time.
It's like he's you're sort of living the movie like he is living in It's like, oh, I'm here, Why am I here?
I don't know why I'm here?
And then you flash back to like thirty minutes ago to figure out how he got there, and then you keep flashing back thirty minutes at a time.
That's the movie.
And this guy like actually lifted.
He just woke up every day and thirty minutes the world was brand new to him.
Speaker 2That's a good yeah.
Speaker 3Yeah, And I don't know if that's like terrifying or kind of awesome, but now I think it's terrifying.
Speaker 2I don't think it would a good way to experience the world.
Speaker 4Well, it wouldn't make you useful for pretty much anything except subject There's.
Speaker 3There's something to be said about, like, you know, if we could just wipe our memories or do a little reset.
Speaker 2But no, I'm sorry not making life.
Speaker 3This is a very very serious condition, but one that shut up lot of light on some things that didn't require people to go necessarily digging around in people's brains, right.
Speaker 4Right, right, yeah.
In particularly, she had a lot of light on how memory works in our brain, so, like before this patient, mostly people thought that memory was something that was spread across your brain, Like people thought your brain was used to giant kind of a computer ship and you had just like you know, you store memories in a little bit here, a little bit there, a little bit everywhere.
It's just kind of like evenly spread out.
But what was fascinating about patient HM is that he could remember his childhood, his early adulthood.
He couldn't make me memories, but you could teach him motor skills like he could.
Yeah, Like you could teach him how to play tennis, and the first day he would be terrible at it, but if he kept practicing, he would get better at it, but he wouldn't remember having practice.
Speaker 2Wow.
Speaker 1So every time this guy, for example, plays tennis, he's just a little bit better, right, but he doesn't know why.
Speaker 2He's just really good at it.
Speaker 4Yeah, Like you know, by session thirty, I imagine, right, this is hypothetically because I don't think they really has them to play tennis, But like by session thirty, he'd be like, you know, hitting aces and returning loves and he'd be like, oh my god, I had no idea I could play tennis.
That was basically his experience.
Speaker 1I hope he has a I hope he has a lived perception that he is a virtuoso.
You know what I mean, because it's always the first thirty minutes that he's played tennis.
Speaker 4Yeah, right right, But then in the next session if he doesn't play tennis, he has no idea he's good to play tennis.
Speaker 1Al true periodic victory.
Speaker 2Yeah, real conundrum.
Speaker 3So what did this teach us though about the brain?
That there are certain things that could not be recalled, but yet certain things had a bit more of a sense memory perhaps.
Speaker 4Yeah.
Mainly what it taught people is that there are different kinds of memory.
Like I think most people who are listening to about short term memory long term memory.
So those are two separate things in your brain.
But for a long time, we didn't know that, and we didn't know there was such a thing as motor memory.
Like when you like your signature, you can do you write your signature without thinking about it.
It's just in your muscle memory.
Or some people can play the piano with is your muscle memory.
So that's in a different part of your brain than the long term.
The short term even your verbal and language all that is just in separate areas.
It's still in areas, but it's a little bit more spread out of the brain.
And so that's kind of what it unlocked for scientists is like, oh wait, memory is not just this like one hard drive.
It's like a whole bunch of little hard drive and a whole bunch of different ways that memories gets stored.
Speaker 1So that teaches us as well about that reminds us of things like what is it called broksophasia or something?
So patient HM was capable of retaining and speaking the language she had learned in his childhood.
What we're talking about, we talk about brocos of phasia is of course the breakdown of as you said, Jorge, a different version of the hard drive, right, the one that controls linguistic aptitude.
Did he I don't know the answer.
I'm asking honestly, did sense memory impact anything?
Speaker 2Like?
Speaker 1Could he the same way he was hypothetically taught to be good at tennis?
Could he be taught to and we're breaking tons of ethical experimentation laws on this, but could you possibly teach this patient to be avoidant of or attracted to, say, a certain stimuli like a smell and then wait for that reset in the brain function.
You know, is this guy?
Is it possible to make a world where this guy is waking up experiencing lucidity every thirty minutes and now he just hates the No, what's a good smell to hate?
Oh, my gosh, the smell of coffee, like coffee, coffee, coffee is a great one.
Is it possible to uh, would it be possible to teach sense memory in an olfactory way or what does that take?
Right?
Speaker 4I think the idea is that he couldn't make long term memories, so and I'm not sure that like our associations with certain smells, I'm not sure quite sure where that is in the brain.
So it might some of it might be in our long term memory, in which case he couldn't.
You couldn't train that in him.
But some of it might be automatic, in which case you probably could.
Speaker 2Yeah.
Speaker 1That is fascinating, and it occurs in step with we wanted to ask you about this with another pivotal moment in neuroscience understanding and and folks, by the way, I feel like we've been very very clear about this.
Do not try this at home, no matter how mad you are at your sibling.
Do not try this at home.
Speaker 2Right.
Speaker 1There is another case that occurred in the eighteen hundreds, so a little bit prior to HM, the infamous Phineas Gauge.
Speaker 2Yes, yeah, railroad tie.
Speaker 1Yeah yeah.
Speaker 4So Finished Gage was a railroad worker.
He's just a regular dude in eighteen mid eighteen hundreds up there in Vermont, and you know, by all accounts, he was a nice guy, you know, lived his life, worked hard.
One day, he was like installing these long metal rods on a rock to make way for like a railroad.
And what they do is they pack some dynamite in there, they stick the rod, and then they light the fuse and then that blows up the rock.
What could go wrong?
Right, thing exploded on him and this meter long iron rod basically went through his head.
So he kind of went in through his left cheek, kind of up and above, kind of behind his eyeballs, through the front part of his brain, and then it came out the top.
Gar He did not.
He survived, that is the fascinating thing.
And so he got better and everyone's like, oh, oh my god, that's amazing.
He's a miracle.
I guess the brain is not that important.
For take away.
Yeah, for a long time, he was basically used as an example of like, oh, the brain is like, you know, just one big amorsive most mass, and if you lose a little bit, it's like, you know, you lose a little bit, but whatever, your brain has the risk of itself to like make you who you are.
And so he's revived.
People thought he was fine, but literally little people sort of realized there was something a little off about him, like he quite wasn't quite himself like he reportedly, he just had like a he kind of basically became an a hole.
Speaker 2I don't know if I can say that.
Speaker 1Yeah, he had a he had a market change in his temperance, right he was he was now seen as yeah, like you said, a whole and thank you for keeping it a family show.
Speaker 4But he was not a nice guy.
Not a nice guy.
Speaker 2Oh by all accounts.
Speaker 3Before that though, he was a perfectly nice fellow, a hard worker, like you said, and in fun and fine to be around, jovial.
And then after this people started noticing that something in his personality had shifted.
Speaker 4You know, Yeah, his personality had shifted from being like a nice guy to like being very ill tempered, like he just grumpy all the time.
But and then beyond his personality, he also kind of had a little bit of ADHD now, like he could he find it hard to focus, He couldn't really concentrate, and so he's just he was just kind of like a frustrated person all the time.
And you know, people who knew me were like, this is not the same person.
And so only later when the people realize, like, oh, this is perfectly explained because the front part of your brain, that's kind of where your personality is and where your ability to focus is.
So that was another big part of kind of like mapping the brain and figuring out that there are parts to it that do different things and which parts do different things.
Speaker 3I gotta say, there's a really great episode of our sister podcast, Stuff You Missed in History Class, all about Phineas Gage back in the Archives.
I remember back when I produced that show, that was the first time I'd heard of him, and I thought it was super fascinating.
So do check that one out for a deep dive on this fascinating character.
Speaker 1Also fascinating to borrow that word there.
It's also fascinating that his treating physician was a guy named jam Horlow and jam Harlow, like many Western physicians of his day, held in abiding interest in phrenology.
So maybe if you are, if you are a boffin or a doctor of the day, maybe it's not the fact that this meter long rod went through the front part of this human brain, it's that it altered the shape of the cranium.
So now he doesn't have good guy bumps.
Speaker 4Well, what's interesting is that, you know, this idea sounds crazy, right, like you could judge how a brain works by how well brain is good at something by its shape.
But that's actually something they found kind of in the nineties early two thousands, was that they looked at brain scans of taxi drivers in London.
Speaker 2The knowledge, yeah, the knowledge of this, the way it sort of changed the pathways, right.
Speaker 4Yeah, yeah, So they studied the brains of taxi drivers in life then, and they talk about the knowledge, right, like, you know, if you're brand new at driving a taxi in London, you're clueless.
You have no idea where anything is if you've ever been there, there's like alleys everywhere with all these it's impossible to navigate.
But once you've done it for a while you know, the whole day of the land, you can take anyone anywhere.
They studied the brains of these people, and they found that people who've been doing it for a long time, that part of your brain that stores like locations and spatial memory that's actually bigger, like it grows.
Speaker 2The mind is shriveled.
Y'all.
I'm so bad at directions.
I have no sense of geography.
Speaker 3It's really bad because yeah, because maybe it was, it's been bad even since before, you know what.
It's just funny though, I will say this, I have recently been trying to actively not use maps, and I have found that it improves my sense of direction overall.
Speaker 2So I think it can be almost relearned or you know, improved.
DuPont.
Speaker 5Yeah.
Speaker 2Yeah.
Speaker 4My wife just talked to a coworker who said he's taking his son out for walks just to teach him how to go on walks.
Speaker 2Yeah.
Yeah, he's and it's not always inherent, you know, Yeah.
Speaker 4Because he's going out to college and you know, kids do they basically maybe don't have that ability to walk around.
Speaker 1Yeah.
I haven't had to uh be lost in the woods, right like our four bears.
Uh Yeah, It's funny.
It's funny you say that because we we've talked in the past about these arguments regarding you know, regarding the advent of offloading uh, some sort of process right from the human machine to an external machine.
And I love that you're bringing up the knowledge because that was a revolutionary study in neuroscience.
It reminds me as well of a study I want to say it was in Why You in two thousand and eight, admittedly small sample size, but they studied people who meditate, Buddhist monks in particular, and they found something similar similar to the similar to how the use of the part of the brain that is occupied with spatial positioning appropreception.
You could argue, similar to how their continued practice of knowing where they are and where they're going literally became mind over matter and increased the I believe the argument is not just the increase in size, but the increase in density of synaptic connections.
The study in eight with Buddhist monks found, and I'm going to sound so pops, I hear, and I apologize, it found that the part of the brain position toward or associated with things like empathy and compassion was actually denser and larger and exhibited more activity in those Buddhist monks versus a sample size of you know, jerks like.
Speaker 4Us, non Buddhist monks, not.
Speaker 1Enlightened, not yes, not enlightened, perfect diplomacy.
So this brings us to I think I think the general umbrella term for this concept is neuroplasticity.
Is that what we're kind of talking about?
What is neuroplasticity.
Speaker 4Yeah, it's kind of this idea that your brain is not static, like at all, Like your brain is constantly kind of rewiring itself, kind of constantly tuning itself.
And it's not like you're necessarily growing new neurons, but these neurons are making new connections between themselves.
And also kind of more importantly is that these the connections that they have, they're constantly kind of recalibrating themselves.
And actually that's kind of what's happening.
That's how like ais learn.
You know, if you look at these neural net models, basically what they're changing when they're learning stuff is the weighing of the synaptic connections.
So like how strong priority wise or yeah kind of priority wise.
Yeah, Like each neurons is connected to like let's say a hundred other neurons, and like it's getting all these inputs, so which ones do you ignore?
Which ones do you listen to?
And so that happens at what are called synapses, which is kind of where like you know, the little branches of two neurons kind of mean.
Speaker 2And firing, right, firing synapses.
Speaker 4Firing, yeah, firing synapses where that gets transmitted from one to the other.
So that's that's where that's happening.
Speaker 3Yeah, And when you look at a brain scan or an MRI, if I'm not mistaken, you can literally see this activity right lighting up in different regions of the brain.
Speaker 4Kind of these these are like almost like molecule size.
They're like super super tiny, so you can't see them like an MRI, but you can see kind of like when you're looking at MRI, what you're looking at is like the oxygen consumption of your neurons.
So you can tell like, oh, these neurons are being active because they're God, drinking.
Speaker 2Up a lot makes a lot of sense.
So it's an indicator, got it.
Yeah, Yeah, that's fascinating.
Speaker 1So now we have learned that in given that the universe observable according to Big Bang theory is about fourteen billion years old.
Humans are real up and coming fad overall.
Speaker 4Right, we're the latest it beings.
Yeah we are, We sure are, and for long.
That's how fads work.
Speaker 1And and we we also learned in that very brief span of time that we call humanity.
Uh, people went from totally thinking the soul was in the most protected part of the body, the torso right to figuring out, oh, that fatty thing in your head does something.
Right after we figured out just how to stop eating each other's brains.
Uh, just gonna throw that in there, and and and then from there we see this, this vast series of at times problematic innovations, sometimes based in accident, sometimes based in confirmation bias or as you said, quack science of phrenology or hate.
Where does the exploration of consciousness and neuroscience go in the future, By the way, just going to put this out there for posterity.
Jorge, Noel Max and I are recording this on Monday, June twenty third, twenty twenty five, So no pressure, Orge.
Next thousand years, where are we at.
Speaker 4No set, assuming we survived the next I don't know months, Oh my god, existence here you know.
I think these things are like Pandora's blogs.
You know, once you open them, you can't go back, you know.
And so I think we're going to be understanding the universe a lot more, We're going to be understanding things at the quantum level a lot more.
And who knows what's going to happen with AIS.
You know, it's quite I think possible that within I don't know, twenty years, there'll be a conscious AI who is smarter than us.
Speaker 3I think can That is the term that gets thrown around a lot, is singularity in terms of AI.
But then we also in talking about the Big Bang that's referred to as a singularity event, and maybe the terms are sort of used loosely, But can you kind of talk about that term and how it applies to both of those different things.
Is it really just kind of like an it moment where a big thing happens.
Speaker 2Yeah.
Speaker 4So consciousness is one of the most debated things in like neuroscience psychology.
Like if you ask any scientist like what is even consciousness?
You'll get one hundred different answers.
Some people think it's like totally kind of biologically based, like it's you know, a dog can have some kind of consciousness and can have a little bit of a consciousness, you know, machine can have a consciousness the material materialist philosophy.
Yeah, yeah, exactly.
And some people think there's something kind of special and almost supernatural about it, you know, even scientists sometimes think that when it happens, it's like this kind of indescribable thing that happens.
Speaker 1Yeah, Promethean lighting in a bottle.
Yeah, And this is where we get to the vast precipice, some would say, or the vast horizon, depends upon your interpretations of as you said, Nol, singularity or transhumanism and future futurism.
Nolan and I were talking off air or at length about the concept of AI, artificial intelligence large language models.
We touched on it naturally a little bit in part one, but perhaps we close out chapter two of our conversation on the history of brain science by exploring the nature of AI just a bit further.
Now you have you have, through your work explore human human computer interaction in depth, right and yeah, and so where do you see the future of human interaction with AI going?
You already said, you know, there is a horizon where this kind of thing exists.
What will that tell us about the human brain?
Oh, my goodness, small dog.
Well, it kind of depends on where you land about how special the human brain is.
You know, like I personally am an engineer by training, and to me, brains are really just like meat machines.
You know, It's like it's mechanical, there's chemicals, involves some people think like quantum physics and quantum and certainly plays a role in like those little tiny synapsis that we have, in which case, you know, there is maybe some magic to how the human rain works.
Speaker 2I think we're all made of star stuff.
Speaker 1Well, if the Big Bang is true, then technically that that's also true, right.
Speaker 3Well yeah, we arose from something like that, right, and we had to have.
Speaker 4Yeah yeah, well most of our the atoms and our bodies were made inside of a star.
Yeah, because the universe at the beginning was just all hydrogen, and so anything other than hydrogen was basically made by a star and usually starts dying.
Speaker 1So yeah, this podcast brought to you by hydrogen.
So we're saying then that the nature of consciousness is still something that the world's smartest people past, present, and possibly future have debate, have debated, right, the materialist view of this one thing in this one case, these physical processes, these mechanics, and these chemical interactions, and then there's the larger question is there something bigger?
Right?
Is an individual consciousness only a node for a larger system which gets little It's a lot of my old professors hate that idea.
Speaker 4Yeah, it's this idea like humans are the way that the universe understands itself kind of.
Is that what you're talking about a little bit, Yeah.
Speaker 1Because you're talking about we're talking about now what we would call Homo sapiens exceptionalism, right, yeah, right, the idea that although one can observe perhaps emotions in a pet, or what seems to be emotions in a pet, even on the strength of various cognitive diagnostics, you could observe maybe the way an octopus dreams, or the the functions of certain higher order mammals.
Speaker 3To take what we're talking about metacognition here, right, like the fact that humans are uniquely built to think about thinking, to analyze themselves, sometimes into oblivion, which is why maybe sometimes I'm jealous of the guy that can't remember anything for more than thirty minutes, because it can be a awaking nightmare at times what we do to ourselves in terms of like thinking about thinking and all of the possibilities, and it can be really exhausting, right.
Speaker 4Yeah, yeah, And they're fascinating cases in the history of brain science to the kind of speak to consciousness.
So one fascinating case that is pretty recent are conjoined twins.
So there's a pair of famous twins called the Hogan twins, and these are two girls who were born conjoined were they basically share a brain, or they share parts of the brain, and specifically they share like this part called the thalamus, which is kind of like a kind of a hub inside of your brain kind of relays information and so it's too definitely to people, like you can talk to one of them, you can talk to the other of them.
But they sort of share their consciousness almost in a way like like one of them can sense what when the other person.
Sometimes one of them can sort of sense what the other person is thinking, and they can sort of each control different parts of the other person's body kind of like one of them controls the left leg of the other one, the other one controls the right arm of the other one.
I forget the exact details, but it's kind of like, like you said, kind of like we sometimes think being conscious the only way to be conscious is to be conscious like humans are right now, But there are other ways that we can be conscious.
Speaker 3Well, I mean, even other non conjoined twin studies yield some pretty interesting results, like in terms of potentially some kind of link, you know, where there's at the very least a what's the word I'm looking for, a kind of intuition, you know, in terms of like that would you know, surpass normal intuition maybe between regular siblings.
I've met known in my life multiple sets of identical twins, and there's something to it.
Speaker 2It's very fascinating.
Speaker 3I would say that is a different kind of consciousness in some ways where you are.
Maybe it's a product of sharing the same space so much and you know, spending so much time around each other.
But I have seen something, some things that have a hard time explaining in terms of the way twins can kind of know what each other are thinking and feeling.
Speaker 4Yeah, I mean, there's definitely a role for intuition there, and you know, it doesn't have to be physical consciousness, Like you know, I kind of personally think that we all kind of share as a human species some sort of consciousness.
Speaker 1You know, through the collect it's unconscious, Yeah, like the young and super consciousness, right right, Like that just.
Speaker 2Adds to that.
You're right.
Speaker 3I'm sorry I didn't interrupt, but that's a really good point.
The Internet is, in and of itself, a super scaled version of that just contributes to what we're talking about.
Speaker 4Yeah, it just really all depends on how you define this word consciousness.
Speaker 2Mm.
Speaker 4Like if it means, like, you know, being able to write poetry and understand Shakespeare, that's one you might not get very far there.
But you know, I've talked to scientists basically, just define it as our sense are as one of our senses that keeps track of our internal state.
So like you have a visual sense that tells you, oh, I'm in the room, there's a door over there, that's an apple over there.
You have kind of an inner looking sense that just tells you like, oh, I'm feeling this way, I'm thinking about this, I'm having this memory of the apple eight this morning.
It's just kind of like something that tells your body, Oh, this is what's going on inside your brain.
Speaker 3Well, the key word there also is I you know, and this idea of identity and this idea of consciousness revolving around.
Speaker 2Who we are and when who we are.
Speaker 3Being ultimately a collection of experience is that are in many ways influenced by the society we live in and you know, and if you want to take it further than them people trying to achieve enlightenment, the idea is sort of disconnect from all of those aspects and like truly experience the spiritual part of what it is to have me have a soul or to like, you know, what it means to be part of the universe, rather than this identity, this construct that we sort of you know, force upon ourselves or is forced upon us oftentimes.
Speaker 2It's fascinating.
Obviously I'm super into this.
Speaker 4Well did this gets We just did an episode about this on Signed Stuff, the podcast on and about near death experiences.
Speaker 2Oh, we just.
Speaker 3Talked to an incredible podcast creator and friend of the show, Dan Bush on stuff that I want you to know about his incredible podcasts Alive Again.
That is all about interviews with folks who've experienced your experiences.
Speaker 1I'm going to connect you with those folks.
You guys should hang out can you tell us just a bit of a tease as we wrap up what you found in your explorations on ND or near death experiences in science stuff.
Speaker 4Yeah, well, it kind of goes back to this idea of what consciousness is and because you know, a big part of near death experiences is this out of body experience.
People feel like they're outside their body, and what we found was that it can it can all be explained by science by how your brain works, and but whether that's actually what's going on, like you know, scientists can't answer that because you know, we can't test someone while they're having it experience.
But basically all of these phenomena near thats you know, feeling outside of your body, having weird visions, talking to people who are already dead, there are brain processes that you can say, Okay, I think that's what's going on there, and that we can replicate that in the lab.
If I give you, you know, a hallucinogen, well in a control environment, you're also going to have these experiences.
If I take i'm achine that disrupts this part of your brain, I can make you feel like you're stepping outside your body.
Speaker 1Or experiencing divinity like the famous god helmet experiments, and and also very well done doctor cham to note that we cannot ethically pursue some direct experiments that would lead to breakthroughs there because it would require doing kind of evil things to innocent people, even if they signed up.
You know, we've all seen flatliners.
Yeah, classic Julia Roberts movie.
Yeah, oh yeah, that was joy, that was yeah, young Sutherland, Yeah yeah yeah.
And uh, you know, I've got to be honest.
Uh, it's a super up to date pop culture reference, I'm sure, but I remember seeing flatliners and being convinced that this is why people join med school and.
Speaker 2So they can do the flat so they can do flatliners.
Speaker 1Yeah.
Luckily, Luckily, my uncle, a very nice, very learned man, assured a young Ben Bullen that it would still be illegal to quote unquote flat line people to quote unquote see what happens.
Speaker 2Well, And speaking of other cinematic masterpieces, we were talking a little earlier about the idea of Vibes, and I have to take this opportunity to recommend the movie Vibes.
Oh my god, it's one of your favorites, Ben.
I actually recommended it to a friend the other day.
Speaker 3Seminole Ghostbusters slash Indiana Jones mashup slash Ripoff that everyone should see, starring Jeff Goldbloom and Cindy Love Hare, No True No Vibes.
Well, get you to a cinema or hey, hopefully they're doing a revival screening of Vibes somewhere in your neck of the woods.
Speaker 4I think I missed that seminal moment in neuroscience.
Speaker 2It's okay, Yeah, it explains a lot.
It's a real breakthrough.
Speaker 1It's sort of like the Police Academy four of its time.
Speaker 2It's probably contemporary with Police Academy.
It probably is.
Actually I've come out the same year with that.
Speaker 1Thank you so much, Orgee for spending time with us and making this Orgey and Science Stuff Week.
Where can people learn more about your explorations.
Speaker 4Yeah, so right now my big project is sign Stuff.
It's a new iHeart podcast.
You can find it anywhere you get your podcasts.
Search for sign Stuff one word and look for the purple icon.
That's us.
And we asked her awesome questions like do animals understand death?
Or do they like to get drunk?
Or what's inside of a black hole?
Or oh, grow limb Yeah, that's the one that was super fascinating recently.
Why can't we regrow limbs?
There are animals who, like you, cut up their arm, don't just grow a brand new one.
Why can't we do it?
And we find out the answer is maybe we can.
Speaker 1And while you are on the internet, please do check out one of our favorite aspects of Doctor Chimp or Hey.
In addition to being one of, if not the smartest people on the history of this show, definitely in this episode.
You are not just a mechanical engineer Stanford graduated.
You did not just attend Georgia Tech, one of the most difficult schools of its caliber.
You are also the creator of a comic strip called PhD Comics.
Could you tell us a little bit about that?
Speaker 4Yeah, PhD Comics.
You can find out a PhD Comics dot com.
It's a comic strip I started when I was in grad school, and it's all about what it's like to do science, what it's like to be an academic.
It's kind of people describe it as the Dilbert of academia.
Speaker 2I don't know this, guys.
I'll have to check it out next trip in my life.
Speaker 4Yeah.
Yeah, and so I was super lucky to be able to do that for many many years on the internet, huge amount of support for people out there, and then that translated to me doing movies and then a TV show.
Recently you can find that one on PPS Kids.
It's called Eleanor Wonders Why.
And I've also gone in to write and draw a lot of books.
So my probably my most famous one I've worked on is called We Have No Idea, which is a guide to everything we don't know about the universe.
And now the most popular one is something called Oliver's Great Big Universe, which is for kids.
If you have a kid who's really curious and like science but also likes, you know, far jokes and really fun, fun middle school middle grade stories, please check it out.
Speaker 3A polymath and renaissance man, indeed, doctor Horte Sham, thanks again for joining us on Ridiculous History.
Speaker 5For Hoorte Sham week, oh thank you, and well well well bully for us, congratulations and tally ho Wecei Thury, Yes, Noel we once again, my friend, uh.
Speaker 1We managed to speak with a world class expert uh in science, and I think we post some interesting questions.
Speaker 3I think so, I think we held our own with doctor cham Jorge to his friends.
I'd like to think that we walked away from these recordings as friends.
He said, like said, he wanted to come back on again, and that we made him laugh and smile.
Speaker 2That made us feel really good.
That's true.
Speaker 5Our neurons were firing, were they which whichever part is associated.
Speaker 1With learning and with us?
Speaker 2And joy?
Speaker 1And joy?
That's the word we were looking for.
Uh we I don't know.
No, this guy is so close to getting a cool ridiculous history, street name, a nickname, an operator name.
Speaker 2You know it's doctor horget riverside Champ.
Oh, that's true, he made his own.
Speaker 5There we go.
Speaker 3Now we can do better, we'll workshop that one, but for now.
Huge days to you, Ben.
That was a fun exploration of all things heady and universal.
Speaker 1Huge thanks to you know, huge thanks to our super producer, mister Max Frictionless.
Williams got a nice haircut there.
Also, big big thanks to aj Bahama's Jacob's Jonathan Strickland aka the Twister.
Okay, yep, big thanks to him.
Speaker 2Oh yeah, of course.
Sure, the rude dudes over a ridiculous crime.
Speaker 3We've got Chris Praciota's and Eve Jeff Coates here and Spirit you know what, I think.
Speaker 4We'll see you next time, folks.
Speaker 3For more podcast from iHeartRadio, visit the iHeartRadio app, Apple Podcasts, or wherever you listen to your favorite shows.