Women can lose up to 20% of their bone density during perimenopause—and most don’t even know it’s happening. In this episode, orthopedic surgeon and author Dr. Vonda Wright breaks down how aging, hormones, and lifestyle impact bone, muscle, and brain health, and shares practical steps to stay strong, resilient, and unbreakable. From hormone therapy to lifting weights, she reveals the science-backed strategies that help women thrive at every stage of life.

About the guest:

Dr. Vonda Wright is a double-boarded orthopedic surgeon and leading authority on active aging and mobility. Her practice spans minimally invasive hip, shoulder, and knee surgery, cartilage restoration, injury prevention, and performance optimization. As founding director of PRIMA, her groundbreaking research on musculoskeletal aging is reshaping how we approach longevity and mobility. Dr. Wright has cared for athletes across the spectrum—from Division I teams and Olympic track athletes to World Rugby, the Atlanta Ballet, and even E-Sports competitors.

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Where to find Dr. Vonda Wrighthttps://www.drvondawright.com/

Instagram: @drvondawright

Pre-order her new book: https://theunbreakablebook.com/

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I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics.

My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention.

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Topics discussed:

00:00 – Intro

01:15 – Aging, Hormones & Bone Density after 30

05:35 – Defining Frailty & “Unbreakable”

09:15 –  Underlying message & Practice Insights

13:54 - Muscle vs. Sedentarism

17:00 – Bone as an Organ

20:00 Bone Hormones & Brain Health

27:00 - Osteoporosis Risks & Prevention

32:20 Bone Quality vs. Density

37:23 – Estrogen, Inflammation & Musculoskeletal Aging

46:09 – Personal Story of Perimenopause

51:03 – Politics of Women’s Health

1:07:00 – Supplements for Bone Health

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