Baseball fans around the country are on tenterhooks—waiting to see if the Toronto Blue Jays will win the World Series. A win tonight or tomorrow will seal the deal.

And: U.S. President Donald Trump says he’s not resuming trade negotiations with Canada any time soon. He’s still angry about an ad by the Ontario government using a Ronald Reagan speech about tariffs. Trump says Prime Minister Mark Carney apologized, but that’s not enough to restart talks.

Also: Food, drugs, alcohol, motivation—research suggests GLP-1 drugs could blunt your desire for all those things. And scientists are trying to figure out how to balance the positive effects with the negative.

Plus: Carney meets Xi, the risks of intravenous therapy, a view of Gaza, and more.