World Heart Podcasts
·S5 E7
Mendelian Randomisation in Cardiovascular Research - Assumptions, Pitfalls & Practice
Episode Description
Host Pablo Perel and co-host Prof. Raul Santos talk with Dr Jiao Luo about Mendelian randomisation (MR) in cardiovascular research, what it is, core assumptions (relevance, independence, no horizontal pleiotropy), common pitfalls (weak instruments, population mismatch, non-linearity), and how to read MR papers.
The episode references:
Mendelian Randomisation: Concepts, Opportunities, Challenges, and Future Directions.