Sharon and Scott return to TWiV for a Zika virus update, including their work on viral evolution and spread, and whether pre-existing immunity to dengue virus enhances pathogenesis.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler

Guests: Sharon Isern and Scott Michael

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Links for this episode

• Hurricane Zika (TWiV 410)
• 454 Corporation (Wikipedia)
• Regional Zika update, Americas (PAHO, WHO)
• Zika virus serum bank (pdf)
• Zika virus evolution and spread in the Americas (Nature)
• Multiple introductions of Zika virus in US (Nature)
• Inhibition of Zika Virus Replication by Wolbachia (J Virol)
• Zika virus pathogenesis in rhesus macaques unaffected by immunity to dengue virus (Nat Commun)
• Impact of flavivirus immunity on Zika virus infection in rhesus macaques (PLoS Path)
• Enhancement of Zika virus pathogenesis by antiflavivirus immunity (Science)
• No ADE by dengue antibodies in Zika virus patients (Clin Inf Dis)
• Oropharyngeal mucosal transmission of Zika virus in rhesus macaques (Nat Commun)
• Letters read on TWiV 454

Weekly Science Picks

Dickson - Industrial Scars
Kathy - Eclipse info by zipcode
Sharon - Michaela's article in The Conversation
Scott - Signal P, Pecaan, Phamerator, DNAmaster
Alan - The Eagle Whisperer" (and the Great Big Story channel)
Vincent - Bottle

Listener Pick

Kevin - Tenure track scientist bites the dust

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv