Clinical trial support companies are rapidly adopting AI, but sponsors have been more hesitant. Raj Indupuri, CEO of eClinical Solutions, gives the top three reasons behind the holdup in AI agent deployment. He explains the specific pattern of uptake for these agents, the required human-in-the-loop oversight, and how the agents can improve clinical trial velocity. Host Deborah Borfitz also gives the latest news on a highly acclaimed treatment for pancreatic cancer, filling evidence gaps in drug safety during pregnancy, guidelines for routinely collected health data for research purposes, an innovative portal aiding bidirectional communication with patients, and more. 

Show Notes 

News Roundup 

KRAS inhibitor therapy for pancreatic cancer 

• Study in The New England Journal of Medicine  
• News on the Fred Hutch Cancer Center website  

Target trial emulation in rural areas 

• Perspective in the Medical Journal of Australia 
• News on the Griffith University website   

AI for improving drug safety during pregnancy 

• Report from the Journal of Medical Internet Research 

Guidelines on the use of routinely collected data 

• Article in The BMJ 

New regulatory framework in the U.K. 

• Press release by the Medicines and Healthcare products Regulatory Agency  

Participant Engagement Portal 

• Article in JNCI Cancer Spectrum 
• Press release from the Alliance for Clinical Trials in Oncology 

The Scope of Things podcast explores clinical research and its possibilities, promise, and pitfalls. Clinical Research News senior writer, Deborah Borfitz, welcomes guests who are visionaries closest to the topics, but who can still see past their piece of the puzzle. Focusing on game-changing trends and out-of-the-box operational approaches in the clinical research field, the Scope of Things podcast is your no-nonsense, insider’s look at clinical research today.