In this classic radio episode, Savage explores the question, "What is truth?" through a mix of politics, religion, immigration, personal experience, and warnings about psychedelics. He and callers discuss psychedelic drugs, including LSD, psilocybin, and MDMA, with callers describing frightening experiences, addiction, trauma, and lasting psychological consequences. Savage questions claims about the therapeutic benefits of psychedelics and challenges the overly optimistic media narratives surrounding them. Savage and callers converse on themes of reality, ego, faith, and human survival and conclude with warning that audiences should remain alert to manipulation and deception.