In this episode of The Mind-Gut Conversation, Dr. Emeran Mayer sits down with Dr. Lauren DeDecker, a board-certified internal medicine physician with training in nutrition and integrative medicine, to explain how gut health is approached in real-world primary care.

They discuss why fiber and plant diversity remain foundational for digestive and metabolic health, how microbiome research reshaped modern medicine, and why popular diet trends often miss the bigger picture. The conversation also covers SIBO, common gut-related diagnoses, and how GLP-1 medications are changing what we understand about appetite, inflammation, and metabolism.

Key Topics Covered:

• Gut health and the brain-gut-microbiome system

• Fiber, fermented foods, and microbiome diversity

• SIBO, overdiagnosis, and gut symptoms

• Popular diets: carnivore, keto, Mediterranean

• GLP-1 medications, appetite regulation, and inflammation

This is a practical, evidence-based discussion for anyone interested in supporting gut health — whether navigating digestive concerns personally or working with patients in a clinical setting.

Please leave any comments or feedback on the episode — we’d love to hear your thoughts.

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Connect with Dr. Mayer:

Website: https://www.emeranmayer.comInstagram: https://www.instagram.com/emeranmayer/X (Twitter): https://www.twitter.com/emeranmayermdFacebook: https://www.facebook.com/EmeranMayerMD/LinkedIn: https://www.linkedin.com/in/emeranmayer/

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Chapters:

0:00 – Introduction to Gut Health & Integrative Medicine

1:30 – From Conventional Medicine to Integrative Care

6:30 – Why Gut Health Became Mainstream (Microbiome Science)

12:30 – Fiber, Plant Diversity & Foundational Gut Health

18:45 – Diet Trends Explained: Carnivore, Keto & Mediterranean

22:30 – SIBO, Gut Symptoms & Overdiagnosis

31:45 – GLP-1 Medications, Appetite & Metabolism

41:15 – The Future of Gut Health & Lifestyle Medicine