Jim talks with James Fadiman and Jordan Gruber about the findings in their recent book Microdosing for Health, Healing, and Enhanced Performance. They discuss the definition of microdosing, "subthreshold" vs "subperceptual," typical doses, current usage statistics & demographics, its legal status & classification history, LSD, psilocybin, why cannabis isn't suitable for microdosing, mechanisms of action, dosing protocols, anti-inflammatory effects, health applications, enhancement applications, contraindications & side effects, research methodologies & limitations, commercial potential, global adoption patterns, and much more.