Eli Lilly is testing a new GLP-1 called brenipatide in phase three trials, and weight loss isn't even the main focus, researchers are watching it for alcohol use disorder, opioid addiction, bipolar disorder, and IBS. Chalene Johnson also breaks down a new Yale University study on why the hunger hormones ghrelin and leptin roar back the moment someone stops taking a GLP-1.

Then Chalene calls out an Instagram account called Baddie Bethany (also posting as Baddie Betty on Facebook), nearly a million followers and Instagram is rolling out a brand new AI content label. She also flags an AI "Dr. Chen" wellness account blending real health facts with false ones to earn trust.

Plus, five new health devices she's watching, including a toilet sensor called Throne, an AI skin scanner called SkinBit, and a caregiving wearable from the founders of Fitbit.

Topics discussed: Eli Lilly, brenipatide, Zepbound, Yale University, ghrelin, leptin, berberine, Baddie Bethany, Baddie Betty, Dr. Chen, Chen Family Wellness, Carrie Sisson, Instagram, Throne, SkinBit, Prenuvo, 3D Radiology, Eight Sleep, Apple, Fitbit, Lufu, Lindsey Clancy trial.

 

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🚨Questions Chalene Wants Your Thoughts on:

• Would a GLP-1 built for addiction, not weight, help you?
• Do you want a button that filters AI content out?
• What is something you do today that AI will likely be doing for you in five years?

 

Related Links:

• Check out AI Accounts @badiebethany  and @chen.family.wellness 
• Eight Sleep: https://chalene.com/coolbed Get $300 Discount
• Luffu Link
• Link to the Yale Study
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• Camp Be More 2027 Registration is now OPEN!! 👉 CAMP

 

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Chapters

• 00:00:00 — Intro: the Lindsey Clancy trial + episode preview
• 00:02:15 — Personal update: Penelope's mastectomy surgery and recovery
• 00:05:39 — Miami penthouse construction saga
• 00:08:18 — New Yale University study: GLP-1s, hunger hormones, and weight regain
• 00:12:10 — Losing weight naturally in perimenopause and menopause
• 00:13:21 — Eli Lilly's new peptide, brenepatide, for addiction and IBS
• 00:19:03 — Calling out "Baddie Bethany," an AI-generated Instagram account
• 00:21:31 — Instagram's new AI content labeling policy (Dr. Chen example)
• 00:28:13 — Instagram's July AI tagging feature backlash
• 00:31:10 — Health tech roundup: Throne, SkinBit, Eight Sleep, Apple, Fitbit's Lufu Link
• 00:45:37 — The 2031 journal exercise: predicting the next five years