Episode Description
What does it take to move epilepsy care forward, from understanding the brain's biomarkers to developing therapies that could change patients' lives? In this episode of Seizure Diaries, our conversation explores the intersection of clinical care, research, and engineering innovation through the work of neurologist and researcher Dr. Greg Worrell and his long-standing collaboration with Cadence Neuroscience. Together, they discuss how scientific curiosity and patient-centered care are driving new possibilities in epilepsy treatment.
Listeners gain background on the unique challenges of epilepsy, particularly drug-resistant epilepsy, where traditional medications may not provide adequate seizure control. The discussion highlights the role of Mayo Clinic's research environment, advances in neuromodulation, and the importance of identifying measurable brain biomarkers to guide therapy. The episode also traces the origins of biomarker targeted stimulation and the collaborative work that continues to shape emerging technologies.
Key takeaways center on how innovation happens in real clinical settings, the value of cross-disciplinary collaboration, and the growing potential of data, sensing technology, and personalized treatment approaches. The conversation reinforces a central theme: progress in epilepsy care depends on combining engineering advances with deep clinical insight and a sustained focus on improving quality of life for patients.
Listeners will hear:
-
An overview of the challenges in treating drug-resistant epilepsyHow neuromodulation works and why biomarkers matter
-
The role of Mayo Clinic's research culture in advancing therapies
-
The origin story of biomarker targeted stimulation
-
Real-world patient impacts and success stories
-
Future directions in sensing technology, data, and personalized care
This episode focuses on clinical experience and research insights. While no specific studies were cited, the organizations and technologies below provide helpful context for listeners who want to learn more.
Resources mentioned in this episode:
Learn more at cadenceneuro.com.
Cadence Neuroscience is developing investigational medical technologies that have not been approved or cleared by the U.S. Food and Drug Administration (FDA) or other health authorities. Any forward-looking statements reflect current expectations and are subject to risks and uncertainties. Actual results may differ materially. This information is for educational purposes
only and does not constitute medical advice or investigational device promotion. Patients should consult qualified healthcare providers regarding diagnosis and treatment options.
Currently, these investigational technologies are only accessible through participation in a clinical trial. To learn more about these investigational technologies and how to access them, talk with your qualified healthcare provider or visit www.clinicaltrials.gov.