When we started this Podcast back in August 2022, we, Calum and David, announced the theme to be “Anticipating and managing exponential impact”. We talked about three sub-themes: Developing the skills of exponential foresight; Distinguishing between scenarios, whether they were plausible or implausible, and whether they were desirable or undesirable; and thirdly, Supporting the community of collaborative exponential foresight. 126 episodes later, as we reach the transition between 2025 and 2026, it’s a good time for the two of us to take stock.

Accordingly, in this episode, we each pick out a number of events from the last 12 months which we see as potential signals of larger exponential impact ahead.

Selected follow-ups:

• An MIT report that 95% of AI pilots fail spooked investors - by Jeremy Kahn
• The Shape of AI: Jaggedness, Bottlenecks and Salients - by Ethan Mollick
• The Road To Superintelligence - by Calum
• AI Doomers, Accelerationists & Scouts - Digital Disruption
• The Economic Singularity - book by Calum
• How can better foresight actually improve the world? - Webinar in the series "From forecasts to levers"
• Disrupting the first reported AI-orchestrated cyber espionage campaign - Anthropic
• Major Neuromorphic Computing projects - listed by Conscium
• Why AI Agent Verification Is A Critical Industry - by Calum
• Climate change and populism: Grounds for optimism? - LFP episode with Matt Burgess
• What's Our Problem? - book by Tim Urban
• OpenAI and Retro Biosciences achieve 50x increase in expressing stem cell reprogramming markers
• Progress at LEVF, December 2025 - by David
• UK Biobank
• The THRIVE Act - Regenerative Medicine Foundation

Music: Spike Protein, by Koi Discovery, available under CC0 1.0 Public Domain Declaration