Navigated to The Biology of Health & Longevity | Top Expert Insights from 2025

The Biology of Health & Longevity | Top Expert Insights from 2025

Dec 28, 2025
1h 1m

View Transcript

Episode Description

👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/

👉 Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. https://sarahmacklin.substack.com/


As we wrap up another incredible year of Live Well Be Well, I found myself asking one simple question. What truly stayed with me?


In this conversation, I’m joined by world-leading voices who helped shape some of the most meaningful discussions of 2025, including:


Dr. Stacy Sims, exercise physiologist redefining how women should train, fuel, and recover


Dr. Andy Galpin, performance scientist translating elite physiology into everyday health


Doug Evans, longevity thinker exploring how nutrition and lifestyle shape long-term vitality


Dr. Iñigo San Millán, physiologist uncovering the role of mitochondria in metabolic health and endurance


Jason Van Blerk, founder of Human Garage, offering a new lens on fascia, movement, and healing


This episode is a reflection not only on science, but on perspective. Across these conversations, a shared message emerged. Our bodies are not machines to override. They are intelligent systems that respond to care, context, and consistency.From female specific physiology and metabolic flexibility to recovery, fascia, and longevity, these voices bring clarity to a crowded wellness space. Together, they remind us that sustainable health is built through understanding rather than optimisation alone.


Here’s What We Dive Into:- How female physiology changes the way women should train, fuel, and recover.


- Why performance science must move beyond one size fits all advice.


- What metabolic flexibility really means and why it matters beyond elite sport.


- How mitochondrial health underpins energy, endurance, and long term wellbeing.


- Why recovery is an active biological process, not simply rest.


- What fascia reveals about pain, movement, and whole body connection.


- How modern lifestyles disrupt our biology and what helps restore balance.


- Why longevity depends more on fundamentals than shortcuts.


Love,

Sarah Ann 💛


***


This episode is sponsored by:NOWATCH: The compassionate health trackerConnecting body and mind with unique stress recovery insights so you can live fully today15% off with code LWBW15 at nowatch.com


***


Let’s be friends!

📷 Instagram: / sarahannmacklin

📹 Subscribe: / @livewellbewellsarah

🐦 Twitter: / sarahannmacklin

📱 TikTok: / sarahannnutrition

💌 Newsletter: https://sarahmacklin.substack.com/


***


Sign up to Sarah’s Compassionate Cure newsletter:Science Simplified, Health Humanised.


Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact.https://sarahmacklin.substack.com/


***


00:00:00 The question that shaped this year end reflection

00:04:18 Female physiology and outdated fitness narratives

00:09:42 Performance science beyond extremes

00:15:06 Metabolic flexibility explained simply

00:20:31 Mitochondria and sustainable energy

00:26:47 Recovery as a biological skill

00:32:10 Fascia, pain, and whole body communication

00:37:58 Longevity through fundamentals

00:43:21 What listening to the body really means


***


Love what you’re hearing?

My small ask is to please rate and review Live Well Be Well. This helps the show expand and allows me to keep producing these with the best quality guests. It means a huge amount to me, so thank you.

See all episodes

Never lose your place, on any device

Create a free account to sync, back up, and get personal recommendations.