Telomeres shorten every time many of our cells divide. Once they become too short, those cells can lose their ability to keep dividing. But what happens if you can lengthen them again?

Dr. Bill Andrews explains how research into telomerase opened that possibility and what happened when scientists restored telomerase activity in experimental cells and mice. He also discusses where gene therapy fits into the picture and the risks that still stand in the way.

This episode is a repurposed segment from an earlier Live Beyond the Norms conversation. Watch the full original episode here: https://www.youtube.com/watch?v=ozDn2tN3Nf4

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Resources Mentioned:

Hayflick Limit - https://www.sciencedirect.com/science/article/abs/pii/0014482761901926 

Geron Corporation - https://www.geron.com/

ClinicalTrials.gov study on AAV-hTERT gene therapy for Alzheimer’s disease - https://clinicaltrials.gov/study/NCT04133454 

About Dr. Bill Andrews:

Dr. Bill Andrews is a molecular biologist and the founder and CEO of Sierra Sciences, where he researches telomeres, telomerase, and human aging. He earned his Ph.D. in Molecular and Population Genetics from the University of Georgia in 1981. As Director of Molecular Biology at Geron Corporation, Andrews was one of the principal researchers involved in identifying the RNA and protein components of human telomerase. He later founded Sierra Sciences in 1999 to continue researching telomere maintenance and its potential applications in human longevity.

Connect with Dr. Bill Andrews:

- Website: https://sierrasci.com 

- Email: bandrews@sierrasci.com 

Connect with Chris Burres:

- Website: https://www.myvitalc.com/ 

- Website: http://www.livebeyondthenorms.com/ 

- Instagram: https://www.instagram.com/myvitalc 

- TikTok: https://www.tiktok.com/@myvitalc 

- LinkedIn: https://www.linkedin.com/in/chrisburres/ 

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