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Unvaccinated Under God: Kira Ganga Kieffer on Religion and Vaccine Hesitancy in Modern America
Episode Description
“Vaccine hesitancy in the U.S. should be understood as religious expression — not as the product of scientific misinformation. These debates have been proxies for existential concerns about justice and morality.” — Kira Ganga Kieffer
Are anti-vaxxers simply bizarre anti-science crazies egged on by conspiracists like RFK Jr? For Kira Ganga Kieffer, author of Unvaccinated Under God, what she calls “vaccine hesitancy” in America is actually a more complicated and prescient affair.
The prevailing narrative — that vaccine-hesitant people lack scientific facts or serve their own individual agendas — misunderstands what’s actually happening. Kieffer’s argument is that vaccine hesitancy is best understood as a kind of religiosity. Not in the narrow context of church doctrine, but in the broader sense of meaning-making, moral reasoning, and an intensely individualist relationship with the body that is deeply rooted in American evangelical and alternative-spiritual tradition.
This hesitancy, Kieffer shows, is not new. It has been present since the smallpox vaccine in the eighteenth century. What recurs across very different eras and very different communities is a set of metaphysical rather than scientific concerns expressed in the language of wellness, purity, and bodily sovereignty.
The most interesting political implication of Kieffer’s argument is that the same hyperindividualistic anti-modern instinct behind vaccine hesitancy also drives the wellness movement, the rejection of AI, and the political coalition that coalesced around RFK Jr. She sees this as a broad and growing constituency that neither party has fully understood nor spoken to. Rather than crazies, today’s anti-vaxxers might offer a window onto tomorrow’s American politics.
Five Takeaways
• Vaccine Hesitancy Is Moral Meaning-Making, Not Ignorance: The dominant public health framing: vaccine-hesitant people lack scientific knowledge. Kieffer’s reframe: they are engaged in profound moral reasoning about the body, purity, parental responsibility, and the relationship between the individual and the state. The parent who fears the MMR vaccine is not asking a scientific question. They are asking: if I consent to this intervention and my child is harmed, am I responsible? That is a theological question — about guilt, intention, and moral agency — dressed in the language of health.
• Evangelical Hyperindividualism Is the Root: Kieffer’s structural argument: American evangelical Christianity is, at its core, an individualist proposition. You are saved by your personal choices. This translates directly into the wellness culture’s logic of bodily salvation: you are saved from illness, aging, and death by your personal choices about diet, supplements, and vaccines. The individual body becomes the site of spiritual as well as physical salvation. This hyperindividualism is very American — and very old. It predates the wellness movement and will outlast it.
• Vaccine Hesitancy Has Been Present Since the Eighteenth Century: Kieffer’s most important historical corrective: vaccine hesitancy did not begin with COVID, with MMR, or with the anti-vaccine movement of the 1990s. It has been present since the smallpox inoculations of colonial Massachusetts. What recurs across very different eras is not the same people or the same science — it’s the same core concerns: bodily purity, parental moral responsibility, and distrust of external authority over the body. Each generation clothes these concerns in the available language. Today it is wellness. Earlier it was religious freedom.
• RFK Jr.: Evangelical Crusader or Wellness Influencer? RFK Jr. shares many characteristics of the evangelical crusader — a sense of special mission, a narrative of persecution, a world divided into the awakened and the deceived. But Kieffer is careful not to put words in his mouth. What she observes: in his crusade for wellness and his critique of organised medicine, he channels the same instincts she traces throughout the book. His coalition is now showing signs of disillusionment — followers who believed he was a true believer are finding that political power complicates purity. They are looking for someone else.
• The Anti-Modern Instinct Will Shape American Politics: The same hyperindividualist, anti-modern instinct that drives vaccine hesitancy also drives the rejection of AI, the wellness movement’s critique of pharmaceutical medicine, and the political formations that coalesced around RFK Jr. Kieffer sees a broad and growing constituency that packages distrust of modernity in spiritual terms: what is essentially good is nature, humanity, the unmediated body. Neither party has fully understood or spoken to this constituency. As skepticism about AI and hypertechnology grows, Kieffer expects it to become more politically significant, not less.
About the Guest
Kira Ganga Kieffer is a scholar of American religions, history, culture, and politics. She holds a PhD in Religious Studies from Boston University and is Visiting Assistant Professor of Religious Studies at Fairfield University. She is the author of Unvaccinated Under God: Religion and Vaccine Hesitancy in Modern America (Princeton University Press, May 19, 2026). She lives in Westport, Connecticut.
References:
• Unvaccinated Under God: Religion and Vaccine Hesitancy in Modern America by Kira Ganga Kieffer (Princeton University Press, May 19, 2026).
• Matthew Avery Sutton, Chosen Land: How Christianity Made America and Americans Remade Christianity — referenced in the opening; the preceding KOA episode on American religion.
• Episode 2913: David Ost on Red Pill Politics — the companion episode on the anti-modern political impulse that Kieffer’s book helps explain.
About Keen On America
Nobody asks more awkward questions than the Anglo-American writer and filmmaker Andrew Keen. In Keen On America, Andrew brings his pointed Transatlantic wit to making sense of the United States — hosting daily interviews about the history and future of this now venerable Republic. With nearly 2,900 episodes since the show launched on TechCrunch in 2010, Keen On America is the most prolific intellectual interview show in the history of podcasting.
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