Cindy and Steph discuss a paper that challenges the textbook dogma that B cells must first bind to an antigen for antibody affinity maturation to occur, and a snippet on dysfunctional T cells during bacterial vaginosis.

Hosts: Cindy Leifer and Steph Langel

Subscribe (free): Apple Podcasts, RSS, email
Become a patron of Immune!

Links for this episode

• MicrobeTV Discord Server
• Somatic hypermutation in non-specific B cells (Immunity 2025)
• Dysfunctional T cells during bacterial vaginosis (J Clin Invest 2025)
• Time stamps by Jolene Ramsey. Thanks!

Music by Tatami.
Immune logo image by Blausen Medical

Send your immunology questions and comments to immune@microbe.tv

Information on this podcast should not be construed as medical advice.