The fastest way to reach a live representative at McAfee is by phone. The primary customer service number for US callers is 1 (855) 414-1085 , which operates 24 hours a day, seven days a week. You can also call 1 (855) 414-1085 or 1 (855) 414-1085 . To bypass automated menus, say the word "agent" or press "0" repeatedly on your keypad.