First Take Begins with a breakdown of Thursday Night Football's matchup between the Bills and Lions. Josh Allen and the Bills offense shined for the second week in a row as they put up 41 points on a struggling Lions defense. Are the Bills the best team in the AFC? Next the crew heads to Oxford for what could be the biggest game in college football this season. Lane Kiffin makes his long awaited return to Ole Miss, what should we expect from this game? Should LSU be road favorites? Then the crew looks ahead to week two of the NFL season. The Bears take on the Vikings in an NFC North showdown, who will come out on top? The Jags travel to mile high to take on the Broncos, will Trevor Lawrence continue to ball out? The Ravens play the Saints, will Tyler Shough be able to continue what he did in the second half against the Lions?

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