In this episode of EMRA*Cast's "Bridging Health and Humanity," host Natalie Hernandez interviews Dr. Jailyn Avila about the importance of gender-affirming care in the emergency department. Dr. Avila highlights the significant health disparities and challenges faced by LGBTQIA+ patients, including a reluctance to seek care in the ED due to fear of discrimination and past negative experiences. The conversation covers the critical aspect of treating trans patients with the same respect and care as cis patients, avoiding irrelevant medical questions, and implementing small changes in practice to create a supportive environment. Dr. Avila shares personal experiences as a transgender woman, emphasizes the necessity of advocacy, and provides actionable steps for clinicians to improve the care and trust of LGBTQIA+ patients. The episode also addresses the impact of recent restrictive policies on the health care of trans individuals and calls for education, advocacy, and systemic change to support this vulnerable population.