In this episode, Sam Ashoo, MD and Lara Zibners, MD discuss the August 2025 Pediatric Emergency Medicine Practice article, Diphtheria, Pertussis, and Tetanus: An Update of Evidence-Based Management of Pediatric Patients in the Emergency Department

• Introduction and guest background
• Host welcome, show context
• Dr. Lara Zibners’ credentials
• EB Medicine involvement
• Personal stories and clinical experience
• Memorable tetanus and pertussis cases
• Vaccine advocacy
• Rare disease encounters
• Diphtheria: overview, presentation, treatment
• Toxigenic vs. non-toxigenic, “bull neck”
• Cardiac, neurologic complications
• Antitoxin, antibiotics, public health
• Pertussis: symptoms, vaccine, treatment
• “100-day cough,” apnea in infants
• Waning immunity, boosters
• Azithromycin, treat contacts
• Tetanus: risk, presentation, management
• Clostridium ubiquity, no outbreaks
• Muscle spasms, autonomic instability
• Airway, sedation, antibiotics
• Key ED takeaways and pearls
• Early suspicion, isolation
• ICU admission for severe cases
• Vaccination, reporting
• Resources and article summary
• Appendix, clinical pathway
• ebmedicine.net reference
• CME, further reading
• Guest’s podcast plug and closing remarks
• “Unstable Vitals” podcast
• Where to listen
• Thank you, sign-off

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