Dr. Cassie Smith explains GLP-1 microdosing, insulin resistance, and how lowering inflammation can support sustainable weight loss.

Dr. Cassie Smith breaks down the concept of microdosing GLP-1 medications for weight loss and metabolic health. She explains how small doses can lower insulin-driven inflammation, improve energy, and support sustainable fat loss without triggering severe GI side effects. The conversation explores why obesity is an endocrine disorder, how insulin resistance disrupts hormones and detox pathways, and why optimizing sleep, nutrition, stress, and gut health is essential for lasting results.

Dr. Cassie Smith is a dual board-certified physician by the ABIM in Endocrinology, Diabetes, Metabolism, and Internal Medicine who founded Modern Endocrine after years of struggling with an autoimmune thyroid disease herself. She is passionate about functional and holistic medicine, along with determining the root causes of disease, because of her personal medical journey with Graves disease and Hashimoto’s for years without answers.

At Modern Endocrine, Dr. Smith and her team are dedicated to providing comprehensive and personalized endocrinology care for conditions such as insulin resistance, weight management, thyroid disorders, and hormonal imbalances. Her practice focuses on a 10-step system to repair cellular damage, restore gut health, enhance metabolism, balance hormones, and promote overall wellness through a holistic and preventative approach. Dr. Smith believes in the power of personalized medicine to provide the most effective and appropriate care for each patient. Therefore, Modern Endocrine tailors treatments to each individual’s unique needs by thoroughly understanding each patient’s medical history, lifestyle, and health goals. This information is used along with extensive lab, gut, and genetic testing to customize treatment plans and teach lifestyle modifications. As an expert endocrinologist, she can help any patient struggling with overwhelm make changes to rebalance and align their health.