This is your full video preview of the Detroit Lions vs. Cleveland Browns game in Week 4 of the 2025 NFL season.

Get insight into key matchups, injury reports, betting odds, and what to expect heading into game day. Whether you're a Lions or Browns fan — or just watching the AFC-NFC clash — this breakdown covers everything you need to know.

In this preview:

Top player matchups and position battles

Latest injury news and depth chart change

Game predictions and betting lines

Coaching strategies and potential x-factors