Recorded at the 2026 VIVE conference in Los Angeles, this Beyond Longevity mini-series episode features Mark Zemel, co-founder and CEO of Retia Medical, discussing the company’s hemodynamic monitoring technology that turns continuous bedside physiological signals into real-time clinical insights for high-risk surgery and critical care.

Marc explains Retia’s aim to detect early deterioration, guide diagnosis and therapy, and avoid the unreliability, invasiveness and complexity of older tools, noting deployment in 75 US hospitals and distribution via Medtronic, plus presence in 18 countries.

He highlights FDA clearance for Argos Infinity enterprise software, which extends insights across the hospital and to clinicians’ phones and laptops, and shares a case where rapid detection of falling stroke volume revealed bleeding during AAA repair. The conversation covers workflow-first design, interoperability, cybersecurity, regulatory strategy, and a future path from ICU to broader wards and ultimately wearables for earlier intervention and preventative care.

00:00 Beyond Longevity Intro

00:44 Meet Mark Zeel

01:40 Rata Medical Mission

02:54 Argos Infinity Launch

03:58 Clinicians Want Real Time

05:19 Surgery Near Miss Story

07:20 Why Accuracy Matters

08:42 Why Algorithms Are Hard

10:08 From ICU To Wearables

12:20 Scaling Distribution Globally

13:22 Plug And Play Integration

15:22 Wearables And Data Overload

18:31 Alerts And Clinical Judgment

20:16 AI As Decision Support

21:56 US Versus Europe Markets

23:09 Wearables Beyond EMRs

23:57 Regulation And Cybersecurity

25:07 FDA And AI Pathways

26:50 Clinician Workflow Design

29:39 Bad Data From Friction

31:58 Open Ecosystems Future

33:25 Prevention And Longevity

35:46 Personal Why Wearables Matter

39:24 From ICU To Early Detection

41:44 Rapid Fire And Wrap