The Oscar and Emmy winning actress and Goop founder and CEO reflects on breaking into the business in the 1990s and becoming "the First Lady of Miramax"; working with a generation of great filmmakers early in their careers, including David Fincher, PTA and Wes Anderson; why she grew disillusioned with Hollywood and focused primarily on business for the last 17 years; and what lured her back in front of the camera to play, well, an actress coming out of retirement, opposite Timothée Chalamet in Josh Safdie's latest film.

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