Jo Cheah speaks to clinical pharmacologist Paul Chin about safe use of direct oral anticoagulants and warfarin for adults with atrial fibrillation or venous thromboembolism. They talk about dosing in renal impairment and extremes of body weight, drug interactions, anticoagulant assays, when to use anticoagulant antidotes and when to consult an anticoagulant service. Read the full article in Australian Prescriber.